Subject(s)
Lymphocyte Activation , Tuberculosis, Ocular/diagnosis , Adult , Chorioretinitis/diagnosis , Diagnosis, Differential , Evaluation Studies as Topic , Female , Humans , Keratitis/diagnosis , Keratoconjunctivitis/diagnosis , Male , Middle Aged , Scleritis/diagnosis , Tuberculin Test , Uveitis/diagnosisABSTRACT
The paper presents the results of a combined biochemical study of 111 patients suffering from recently diagnosed pulmonary tuberculosis combined with chronic opisthorchiasis (main group) and 36 tuberculosis patients without infestation (control group). It was established that the mixed abnormality was significantly more often accompanied by hypoproteinemia and hypoalbuminemia. The thymol and mercury-chloride sublimate tests produced positive results in 22.5 and 9.0% of the main group patients, respectively. Increased bilirubin content and alanine and aspartate aminotransferase activities were registered in both groups of patients only during medical treatment. Thus, the fact of altered protein forming function of liver in patients with tuberculosis combined with chronic opisthorchiasis has been established, which may be due both to tuberculosis infection and the Opisthorchis invasion. Insignificant hepatic protein-forming dysfunctions are not contraindications for long-term tuberculosis therapy.
