1.
Small
; 11(23): 2743-9, 2015 Jun.
Article
in English
| MEDLINE
| ID: mdl-25652950
ABSTRACT
Large pore (4.6-7.6 nm) and well-dispersed benzene bridged mesoporous organosilica nanoparticles with uniform particle size of ≈50 nm are prepared via a biphasic approach. They can be directly used as nanocarriers without surface modification for the intracellular delivery of therapeutic proteins.
Subject(s)
Benzene/chemistry , Nanocapsules/chemistry , Nanoconjugates/chemistry , Nanopores/ultrastructure , Organosilicon Compounds/chemistry , Ribonuclease, Pancreatic/chemistry , Cross-Linking Reagents/chemistry , Delayed-Action Preparations/chemical synthesis , Diffusion , Drug Compounding/methods , Humans , MCF-7 Cells , Nanocapsules/administration & dosage , Nanocapsules/ultrastructure , Nanoconjugates/ultrastructure , Particle Size , Phase Transition , Porosity , Ribonuclease, Pancreatic/administration & dosage
2.
Chem Commun (Camb)
; 49(40): 4534-6, 2013 May 18.
Article
in English
| MEDLINE
| ID: mdl-23575377
ABSTRACT
Nanoporous organosilica membranes are successfully coated on porous alumina tubes and tested for desalination via membrane distillation. The membranes produced pure water (up to 13 kg m(-2) h(-1)) across an extreme range of salt concentrations (10-150 g L(-1) NaCl) at moderate temperatures (≤60 °C) without exhibiting the characteristic flux decay of competing materials.