ABSTRACT
Meloxicam (MLX) is a novel nonsteroidal anti-inflammatory drug, but on the other hand, it has become one of the common microcontaminants in surface waters and sewage. Herein, we report the preparation of a ternary-metal Zn(II)-Cd(II)-Eu(III) nanocluster 1 for the response of MLX through the enhancement of lanthanide luminescence. The luminescence sensing behavior of 1 is expressed by the equation I615nm = 3060 × [MLX] + 46,604, which can be used in the quantitative analysis of MLX concentrations in meloxicam dispersible tablets. Filter paper strips bearing 1 can be used to qualitatively detect MLX by a color change to red under a UV lamp. The luminescence response time is no more than five s, and the detection limit is as low as 2.31 × 10-2 nM.
Subject(s)
Anti-Inflammatory Agents, Non-Steroidal , Europium , Meloxicam , Zinc , Meloxicam/analysis , Zinc/chemistry , Zinc/analysis , Europium/chemistry , Anti-Inflammatory Agents, Non-Steroidal/analysis , Anti-Inflammatory Agents, Non-Steroidal/chemistry , Luminescent Measurements , Luminescence , Nanostructures/chemistry , Limit of DetectionABSTRACT
A cube-like Zn(II)-Eu(III) nanocluster 1 (molecular sizes: 1.8 × 2.0 × 2.0 nm) was constructed by the use of a new long-chain Schiff base ligand. It shows a ratiometric fluorescence response to levofloxacin (LFX) with high sensitivity and selectivity, which can be expressed as I615 nm/I550 nm = A*[LFX]2 + B*[LFX] + C. It is used to quantitatively detect the LFX concentrations in fetal calf serum (FCS) and tablets sold in pharmacy. Filter paper strips bearing 1 can be used to qualitatively detect LFX by a color change to red under a UV lamp. 1 and its hybrid with sodium alginate (SA), 1@SA, display potential applications in the qualitative detection of LFX in FCS and the medicine. The limit of detection of 1 to LFX is as low as 2.1 × 10-2 nM.
Subject(s)
Alginates , Europium , Levofloxacin , Zinc , Alginates/chemistry , Zinc/chemistry , Zinc/blood , Levofloxacin/blood , Levofloxacin/analysis , Europium/chemistry , Spectrometry, Fluorescence , Animals , Humans , Cattle , Tablets , Fluorescent Dyes/chemistryABSTRACT
A high-nuclearity Zn(II)-Eu(III) nanocluster was synthesized for the rapid and quantitative luminescence detection of neopterin as an inflammatory marker.
Subject(s)
Europium , Luminescence , Neopterin , Luminescent Measurements , ZincABSTRACT
An interesting 48-metal Zn(II)-Yb(III) nanocluster (1) with a size of about 1.3 × 2.8 × 3.1 nm was constructed by carbonate templates from a Schiff base ligand. It exhibits ligand-centered emission and near-infrared (NIR) luminescence of Yb(III), which are used in the dual-emissive detection of rutin (Rut) with high sensitivity even in the presence of other interferences. The response behavior can be expressed by the second-order equation I980 nm/I510 nm = A*[Rut]2 + B*[Rut] + C, and the limits of detection to Rut for the emissions of 1 are 2.23 µM and 0.20 nM.
