1.
Chem Commun (Camb)
; 2024 Jul 15.
Article
in English
| MEDLINE
| ID: mdl-39007214
ABSTRACT
The current opioid epidemic has incentivized the discovery of new non-addictive analgesics, a process that requires the screening of opioid receptor binding, traditionally performed using radiometric assays. Here we describe a label-free alternative based on high-throughput (1 Hz) ambient mass spectrometry for screening the receptor binding of new opioid analogues.