ABSTRACT
Haemophilus parainfluenzae is a common inhabitant of the human upper respiratory tract of the normal oral microflora. We report three men who had been having unprotected sex with men (MSM) and subsequently acquired H. parainfluenzae urethritis, which was confirmed by 16S rRNA gene sequencing analysis. Two men were treated with ceftriaxone and doxycycline, and the third man was treated with clarithromycin. All three patients responded to treatment. This case series highlights the potential role of H. parainfluenzae as a sexually transmitted genitourinary pathogen.
Subject(s)
Haemophilus Infections/diagnosis , Haemophilus Infections/pathology , Haemophilus parainfluenzae/isolation & purification , Urethritis/diagnosis , Urethritis/pathology , Adult , Anti-Bacterial Agents/therapeutic use , DNA, Bacterial/chemistry , DNA, Bacterial/genetics , DNA, Ribosomal/chemistry , DNA, Ribosomal/genetics , Haemophilus Infections/drug therapy , Haemophilus Infections/microbiology , Homosexuality, Male , Humans , Male , Molecular Sequence Data , RNA, Ribosomal, 16S/genetics , Sequence Analysis, DNA , Treatment Outcome , Urethritis/drug therapy , Urethritis/microbiologyABSTRACT
Time to positivity is an available parameter in automated blood culture systems. We report a patient with persistent methicillin-resistant Staphylococcus aureus bacteremia who received various regimens for treatment of methicillin-resistant S. aureus, and demonstrate that monitoring of the time to positive blood culture might be helpful in the early recognition of treatment failure.
Subject(s)
Anti-Bacterial Agents/therapeutic use , Bacteremia/microbiology , Blood/microbiology , Methicillin-Resistant Staphylococcus aureus/isolation & purification , Staphylococcal Infections/microbiology , Acetamides/therapeutic use , Aged , Bacteremia/drug therapy , Catheters, Indwelling/microbiology , Female , Humans , Linezolid , Oxazolidinones/therapeutic use , Staphylococcal Infections/drug therapy , Time Factors , Treatment Failure , Vancomycin/therapeutic useABSTRACT
Corynebacterium urealyticum, an infrequent cause of bacteremia, is an emerging pathogen in humans, especially immunocompromised hosts. This report describes a patient with prostate cancer complicated with obstructive nephropathy who developed C. urealyticum bacteremia after placement of a percutaneous nephrostomy tube. The bacteremia was not controlled until the infected nephrostomy tube was removed.
