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1.
IEEE J Biomed Health Inform ; 28(5): 3186-3199, 2024 May.
Article in English | MEDLINE | ID: mdl-38412074

ABSTRACT

For a long time, the prevention and control of COVID-19 has received significant attention. A crucial aspect of controlling the disease's spread is the epidemiological survey of patients and the subsequent analysis of epidemiological survey reports (case reports). However, current mainstream analysis approaches are all made manually. This manual method is time-consuming and manpower-intensive. This paper designs an automated visual epidemiological survey analysis (AVESA) framework for the epidemiological survey on COVID-19. AVESA designs a deep neural network for information extraction from case reports and automatically constructs an epidemiological knowledge graph based on predefined pattern. Moreover, a multi-dimensional knowledge reasoning model is developed for conducting knowledge reasoning in the complete COVID-19 epidemiological knowledge graph. In the entity extraction sub-task and multi-task extraction sub-task, AVESA achieved F1 scores of 85.12% and 92.29% respectively on the constructed dataset, significantly outperforming the standalone information extraction models. In full-graph computing, all three experiments align closely with manual analysis standards. In the risk analysis experiment, the weighted PageRank algorithm showed an average improvement of 11.21% in Top_Recall_n% over the standard PageRank algorithm. In the community detection experiment, the weighted Louvain algorithm showed a mere 4.34% community difference rate compared to manual analysis.


Subject(s)
Algorithms , COVID-19 , SARS-CoV-2 , Humans , COVID-19/epidemiology , COVID-19/prevention & control , Neural Networks, Computer , Data Mining/methods , Deep Learning
2.
Curr Issues Mol Biol ; 44(2): 817-832, 2022 Feb 07.
Article in English | MEDLINE | ID: mdl-35723341

ABSTRACT

Large-scale artificial neural networks have many redundant structures, making the network fall into the issue of local optimization and extended training time. Moreover, existing neural network topology optimization algorithms have the disadvantage of many calculations and complex network structure modeling. We propose a Dynamic Node-based neural network Structure optimization algorithm (DNS) to handle these issues. DNS consists of two steps: the generation step and the pruning step. In the generation step, the network generates hidden layers layer by layer until accuracy reaches the threshold. Then, the network uses a pruning algorithm based on Hebb's rule or Pearson's correlation for adaptation in the pruning step. In addition, we combine genetic algorithm to optimize DNS (GA-DNS). Experimental results show that compared with traditional neural network topology optimization algorithms, GA-DNS can generate neural networks with higher construction efficiency, lower structure complexity, and higher classification accuracy.

3.
Brain Sci ; 12(2)2022 Jan 21.
Article in English | MEDLINE | ID: mdl-35203904

ABSTRACT

Small sample learning ability is one of the most significant characteristics of the human brain. However, its mechanism is yet to be fully unveiled. In recent years, brain-inspired artificial intelligence has become a very hot research domain. Researchers explored brain-inspired technologies or architectures to construct neural networks that could achieve human-alike intelligence. In this work, we presented our effort at evaluation of the effect of dynamic behavior and topology co-learning of neurons and synapses on the small sample learning ability of spiking neural network. Results show that the dynamic behavior and topology co-learning mechanism of neurons and synapses presented in our work could significantly reduce the number of required samples, while maintaining a reasonable performance on the MNIST data-set, resulting in a very lightweight neural network structure.

4.
Article in English | MEDLINE | ID: mdl-33799332

ABSTRACT

Accompanied by the rapid economic and social development, there is a phenomenon of the crazy spread of many infectious diseases. It has brought the rapid growth of the number of people infected with hand-foot-and-mouth disease (HFMD), and children, especially infants and young children's health is at great risk. So it is very important to predict the number of HFMD infections and realize the regional early-warning of HFMD based on big data. However, in the current field of infectious diseases, the research on the prevalence of HFMD mainly predicts the number of future cases based on the number of historical cases in various places, and the influence of many related factors that affect the prevalence of HFMD is ignored. The current early-warning research of HFMD mainly uses direct case report, which uses statistical methods in time and space to have early-warnings of outbreaks separately. It leads to a high error rate and low confidence in the early-warning results. This paper uses machine learning methods to establish a HFMD epidemic prediction model and explore constructing a variety of early-warning models. By comparison of experimental results, we finally verify that the HFMD prediction algorithm proposed in this paper has higher accuracy. At the same time, the early-warning algorithm based on the comparison of threshold has good results.


Subject(s)
Epidemics , Foot-and-Mouth Disease , Hand, Foot and Mouth Disease , Algorithms , Animals , Child , Child, Preschool , China , Hand, Foot and Mouth Disease/epidemiology , Humans , Infant , Neural Networks, Computer
5.
Article in English | MEDLINE | ID: mdl-33801219

ABSTRACT

It is very important to have a comprehensive understanding of the health status of a country's population, which helps to develop corresponding public health policies. Correct inference of the underlying cause-of-death for citizens is essential to achieve a comprehensive understanding of the health status of a country's population. Traditionally, this relies mainly on manual methods based on medical staff's experiences, which require a lot of resources and is not very efficient. In this work, we present our efforts to construct an automatic method to perform inferences of the underlying causes-of-death for citizens. A sink algorithm is introduced, which could perform automatic inference of the underlying cause-of-death for citizens. The results show that our sink algorithm could generate a reasonable output and outperforms other stat-of-the-art algorithms. We believe it would be very useful to greatly enhance the efficiency of correct inferences of the underlying causes-of-death for citizens.


Subject(s)
Algorithms , Public Policy , Humans
6.
Brain Sci ; 11(2)2021 Jan 25.
Article in English | MEDLINE | ID: mdl-33503833

ABSTRACT

In neuroscience, the Default Mode Network (DMN), also known as the default network or the default-state network, is a large-scale brain network known to have highly correlated activities that are distinct from other networks in the brain. Many studies have revealed that DMNs can influence other cognitive functions to some extent. This paper is motivated by this idea and intends to further explore on how DMNs could help Spiking Neural Networks (SNNs) on image classification problems through an experimental study. The approach emphasizes the bionic meaning on model selection and parameters settings. For modeling, we select Leaky Integrate-and-Fire (LIF) as the neuron model, Additive White Gaussian Noise (AWGN) as the input DMN, and design the learning algorithm based on Spike-Timing-Dependent Plasticity (STDP). Then, we experiment on a two-layer SNN to evaluate the influence of DMN on classification accuracy, and on a three-layer SNN to examine the influence of DMN on structure evolution, where the results both appear positive. Finally, we discuss possible directions for future works.

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