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1.
Stud Health Technol Inform ; 294: 951-952, 2022 May 25.
Article in English | MEDLINE | ID: mdl-35612254

ABSTRACT

Telemedicine can be useful for diabetes patients living remotely, especially during pandemic times. We aimed to identify current knowledge of the use of telemedicine for diabetes in Norway by conducting a review of the literature. Telemedicine is mostly beneficial, and it seems that it can be adopted into the usual diabetes care in Norway as a low-cost alternative.


Subject(s)
Diabetes Mellitus , Telemedicine , Diabetes Mellitus/diagnosis , Diabetes Mellitus/epidemiology , Diabetes Mellitus/therapy , Humans , Norway/epidemiology , Pandemics , Telemedicine/economics
2.
Mar Drugs ; 11(7): 2655-66, 2013 Jul 22.
Article in English | MEDLINE | ID: mdl-23880935

ABSTRACT

In this paper, we present novel bioactivity for barettin isolated from the marine sponge Geodia barretti. We found that barettin showed strong antioxidant activity in biochemical assays as well as in a lipid peroxidation cell assay. A de-brominated synthetic analogue of barettin did not show the same activity in the antioxidant cell assay, indicating that bromine is important for cellular activity. Barettin was also able to inhibit the secretion of the inflammatory cytokines IL-1ß and TNFα from LPS-stimulated THP-1 cells. This combination of anti-inflammatory and antioxidant activities could indicate that barettin has an atheroprotective effect and may therefore be an interesting product to prevent development of atherosclerosis.


Subject(s)
Anti-Inflammatory Agents/pharmacology , Antioxidants/pharmacology , Peptides, Cyclic/pharmacology , Animals , Anti-Inflammatory Agents/chemistry , Antioxidants/chemistry , Biological Factors/chemistry , Biological Factors/pharmacology , Bromine/metabolism , Cell Line, Tumor , Geodia/chemistry , Hep G2 Cells , Humans , Interleukin-1beta/metabolism , Marine Biology , Peptides, Cyclic/chemistry , Porifera/chemistry , Porifera/metabolism , Tumor Necrosis Factor-alpha/metabolism
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