ABSTRACT
Linear IgA bullous dermatosis (LAD) is an autoimmune, chronic bullous disease affecting primarily young children and adults. Studies on LAD are relatively sparse and from Scandinavia we could only find a few case reports. Therefore we decided to conduct a retrospective investigation of patients seen at our department since 1972. A total of 23 patients were identified; 7 children (F:M ratio 0.75) and 16 adults (F:M ratio 0.78). Mean age at disease onset in the two age groups were 2.7 and 56.8 years. Estimated incidence rate in our region: 0.67 per million per year. The most commonly used treatment modalities were corticosteroids, dapsone and sulphapyridine.
Subject(s)
Linear IgA Bullous Dermatosis/epidemiology , Adult , Age of Onset , Aged , Anti-Infective Agents/therapeutic use , Child, Preschool , Dapsone/therapeutic use , Denmark/epidemiology , Female , Glucocorticoids/therapeutic use , Humans , Incidence , Infant , Linear IgA Bullous Dermatosis/drug therapy , Male , Middle Aged , Prednisone/therapeutic use , Retrospective Studies , Sulfapyridine/therapeutic use , Young AdultABSTRACT
Topical glucocorticoids are the most commonly used drugs for treating a number of acute and chronic inflammatory diseases of the skin and the mucous membranes. Prolonged use of superpotent and potent topical glucocorticoids is related to an increased risk of developing severe side effects. In this case we describe the development of clinical signs of Cushing's syndrome in a 26-year-old woman, after continued daily application of potent topical glucocorticoid in the oral cavity.
