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Article in English | MEDLINE | ID: mdl-33093774

ABSTRACT

Sarcoidosis is a systemic inflammatory disease characterized by granuloma formation in affected organs and caused by dysregulated immune response to an unknown antigen. Sarcoidosis patients receiving immunosuppressive medications are at increased risk of infection. Lymphopenia is also commonly seen among patient with sarcoidosis. In this review, risk of infections, including opportunistic infections, will be outlined. Recommendations for vaccinations and prophylactic therapy based on literature review will also be summarized. (Sarcoidosis Vasc Diffuse Lung Dis 2020; 37 (2): 87-98).


Subject(s)
Immunocompromised Host , Immunosuppressive Agents/adverse effects , Opportunistic Infections/prevention & control , Sarcoidosis/drug therapy , Vaccination , Host-Pathogen Interactions , Humans , Immunization Schedule , Opportunistic Infections/immunology , Opportunistic Infections/microbiology , Opportunistic Infections/virology , Risk Factors , Sarcoidosis/complications , Sarcoidosis/immunology , Treatment Outcome
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