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1.
Unfallchirurgie (Heidelb) ; 125(11): 892-896, 2022 Nov.
Article in German | MEDLINE | ID: mdl-35166880

ABSTRACT

Peripheral nerve injuries are often encountered in traumatological care. The aim of this manuscript is to provide initial data, experiences and performance reports from Germany in the implantation of acellular human nerve transplants in peripheral sensory nerve defects of the hand and to put these data in the context of a comprehensive review of the literature. Of the patients 4 (7 digital nerves) were examined 6 months postoperatively and 5 patients (6 digital nerves) were examined 1 year after the operation (3 were also at the 6­month examination). All patients had a clinical improvement after nerve reconstruction (≥ S3 according to the classification of sensory recovery of the Medical Research Council modified by Mackinnon and Dellon). Disadvantages of our clinical study are the small number of patients, the inhomogeneity (primary and secondary nerve reconstruction) and the lack of comparison with other nerve reconstruction methods.


Subject(s)
Hematopoietic Stem Cell Transplantation , Peripheral Nerve Injuries , Transplants , Humans , Hand/surgery , Peripheral Nerves/transplantation , Peripheral Nerve Injuries/surgery
2.
J Med Case Rep ; 12(1): 333, 2018 Nov 08.
Article in English | MEDLINE | ID: mdl-30404652

ABSTRACT

BACKGROUND: Dilative cardiomyopathy is an uncommon cardiac complication of electric shock. CASE PRESENTATION: We report a case of a 12-year-old German boy with a high voltage injury who developed a four-chamber dilative cardiomyopathy, which was diagnosed on the 13th week postburn. One year after the accident, echocardiography showed a normal function of his heart with 64% ejection fraction and normal cavities' dimensions. CONCLUSIONS: Despite the fact that dilative cardiomyopathy is not very common in electrical injuries but can be fatal, a prolonged echocardiography follow-up for patients with electrical injury could be recommended. Until now this case is the first child with severe burns after electrocution, who developed a reversible dilative cardiomyopathy.


Subject(s)
Burns, Electric/complications , Cardiomyopathy, Dilated/etiology , Cardiomyopathy, Dilated/therapy , Child , Germany , Humans , Male , Treatment Outcome
3.
Plast Reconstr Surg Glob Open ; 6(12): e2011, 2018 Dec.
Article in English | MEDLINE | ID: mdl-30656108

ABSTRACT

Malignant peripheral nerve sheath tumors are rare, associated with a poor prognosis and uncertainty regarding the appropriate management. We report a novel oncologic and reconstructive treatment of a young patient with a malignant peripheral nerve sheath tumor of the median nerve of the left hand. The patient underwent a wide local excision, an opponensplasty, a nerve reconstruction by nerve allografts followed by brachytherapy treatment. Two years later, the patient remains disease free with preserved function of her hand.

4.
Medicine (Baltimore) ; 96(27): e6926, 2017 Jul.
Article in English | MEDLINE | ID: mdl-28682860

ABSTRACT

In the published literature there are controversial data to the biomechanical stability of monocortical comparing to the bicortical fixation of metacarpal fractures. The aim of this study was to compare the biomechanical stability of monocortical and bicortical locking osteosynthesis in quasi-static and dynamic 4-point bending tests of composite third metacarpal bone (4th Gen third metacarpal, Sawbones, Malmö, Sweden) fixed with 7-hole locking plate (XXS System, Biotech-Ortho, Wright, Memphis, TN). The tests to determine quasi-static yield and bending strength as well as fatigue strength were conducted in 4 groups of 10 samples after creating standardized mid-shaft transverse osteotomies using a diamont belt grinder (0.3 mm saw blade). The force applied was the dorsal apex loading, similar to the forces applied to metacarpals during normal finger flexion and extension.In the quasi-static testing, no plate breakage was observed in each group. All metacarpals broke at their thinnest part. The average bending strength of the bicortical samples (10.54 ±â€Š0.998 Nm) was significantly higher comparing to the monocortical samples (8.57 ±â€Š0.894 Nm) (P < .001).In the dynamic loading test, all constructs (8 monocortical samples and 7 bicortical) that failed broke at the osteotomy site and the average fatigue strength did not differ in both groups.Consequently, a unicortical plating method may provide adequate strength and stability to metacarpal fractures based on the results of the cyclical loading representative of in vivo loading.


Subject(s)
Bone Plates , Bone Screws , Fractures, Bone/surgery , Metacarpal Bones/injuries , Metacarpal Bones/surgery , Models, Theoretical , Biomechanical Phenomena , Bone Substitutes , Elasticity , Equipment Failure Analysis , Fingers/physiopathology , Fingers/surgery , Fracture Fixation, Internal , Fractures, Bone/physiopathology , Humans , Metacarpal Bones/physiopathology , Movement/physiology , Osteotomy , Prosthesis Failure
5.
Eplasty ; 17: e8, 2017.
Article in English | MEDLINE | ID: mdl-28293333

ABSTRACT

Objective: Fractures of metacarpals and phalanges are very common fractures, and there are a lot of treatment modalities. The purpose of the study was to describe the technique of percutaneous fixation of phalangeal fractures using a cannulated compression screw fixation system and its results. Methods: We conducted a prospective clinical study on 43 patients with different types of phalangeal fractures undergoing a percutaneous cannulated compression screw osteosynthesis. Parameters such as average operation time and clinical outcome were evaluated postoperatively. Results: Forty-three patients were treated using a percutaneous cannulated compression screw fixation system for phalanx fractures of the proximal (n = 26), middle phalanx (n = 16), or distal phalanx (n = 1). All fractures healed after 6 to 8 weeks except in 1 patient with secondary loss of reduction occurring 2.5 weeks after surgery. No infections were observed. The mean total active motion values were 247.56° ±16.16° and 244.35° ± 11.61° for the intra-articular fracture and 251.25° ± 19.86° for the shaft fractures; the mean Disabilities of the Arm, Shoulder, and Hand (DASH) score 3 months after the surgery was 1.67 ± 2.74. Conclusions: The advantages of this technique are the avoidance of an open procedure requiring extensive soft-tissue dissection with the risks of tendon adhesions and the achievement of interfragmentary compression. Because of the interfragmentary compression, it is superior to simple K-wires. With regard to indications, our primary focus was on unicondylar proximal interphalangeal joint fractures, shaft fractures, and simple oblique 2-fragment fractures.

6.
Ultrasound Med Biol ; 42(12): 2975-2982, 2016 12.
Article in English | MEDLINE | ID: mdl-27662701

ABSTRACT

Elucidation of the precise mechanisms and therapeutic options of extracorporeal shock wave therapy (ESWT) is only at the beginning. Although immediate real-time effects of ESWT on cutaneous hemodynamics have recently been described, the dose response to different ESWT energies in cutaneous microcirculation has never been examined. Thirty-nine Sprague-Dawley rats were randomly assigned to three groups that received either focused high-energy shock waves (group A: total of 1000 impulses, 10 J) to the lower leg of the hind limb, focused low-energy shock waves (group B: total of 300 impulses, 1 J) or placebo shock wave treatment (group C: 0 impulses, 0 J) using a multimodality shock wave delivery system (Duolith SD-1 T-Top, Storz Medical, Tägerwilen, Switzerland). Immediate microcirculatory effects were assessed with the O2C (oxygen to see) system (LEA Medizintechnik, Giessen, Germany) before and for 20 min after application of ESWT. Cutaneous tissue oxygen saturation increased significantly higher after high-energy ESWT than after low-energy and placebo ESWT (A: 29.4% vs. B: 17.3% vs. C: 3.3%; p = 0.003). Capillary blood velocity was significantly higher after high-energy ESWT and lower after low-energy ESWT versus placebo ESWT (group A: 17.8% vs. group B: -22.1% vs. group C: -5.0%, p = 0.045). Post-capillary venous filling pressure was significantly enhanced in the high-energy ESWT group in contrast to the low-energy ESWT and placebo groups (group A: 25% vs. group B: 2% vs. group C: -4%, p = 0.001). Both high-energy and low-energy ESWT affect cutaneous hemodynamics in a standard rat model. High-energy ESWT significantly increases parameters of cutaneous microcirculation immediately after application, resulting in higher tissue oxygen saturation, venous filling pressure and blood velocity, which suggests higher tissue perfusion with enhanced oxygen saturation, in contrast to low-energy as well as placebo ESWT. Low-energy ESWT also increased tissue oxygen saturation, albeit to a lower extent, and decreases both blood velocity and venous filling pressure. Low-energy ESWT reduced tissue perfusion, but improved oxygen saturation immediately after the application.


Subject(s)
Microcirculation/physiology , Skin/blood supply , Ultrasonic Therapy/methods , Ultrasonic Waves , Animals , High-Energy Shock Waves , Male , Models, Animal , Rats , Rats, Sprague-Dawley
7.
Medicine (Baltimore) ; 95(24): e3631, 2016 Jun.
Article in English | MEDLINE | ID: mdl-27310946

ABSTRACT

Bone defects are a very common problem in hand surgery, occurring in bone tumor surgery, in complicated fractures, and in wrist surgery. Bone substitutes may be used instead of autologous bone graft to avoid donor site morbidity. In this article, we will review our experience with the use of Cerament bone void filler (Bonesupport, Lund, Sweden) in elective and trauma hand surgery. A prospective clinical study was conducted with 16 patients treated with this bone graft substitute in our department over a period of 3.5 years. Twelve patients (2 female, 10 male; with an average age of 42.42 years) with monostoic enchondroma of the phalanges were treated and 4 patients (1 female, 3 male; with an average age of 55.25 years) with complicated metacarpal fractures with bone defect. Data such as postoperative course with rating of pain, postoperative complications, functional outcome assessment at 1, 2, 3, 6 months, time to complete remodeling were registered. Postoperative redness and swelling after bone graft substitute use was noticed in 7 patients with enchondroma surgery due to the thin soft-tissue envelope of the fingers. Excellent total active motion of the involved digit was noticed in 10 of 12 enchondroma patients and in all 4 fracture patients at 2-month follow-up. In summary, satisfying results are described, making the use of injectable bone graft substitute in the surgical treatment of enchondromas, as well as in trauma hand surgery a good choice.


Subject(s)
Bone Substitutes/therapeutic use , Bone Transplantation/methods , Chondroma/surgery , Hand/surgery , Orthopedic Procedures/methods , Adult , Female , Follow-Up Studies , Humans , Male , Prospective Studies , Treatment Outcome
8.
J Surg Res ; 201(2): 440-5, 2016 Apr.
Article in English | MEDLINE | ID: mdl-27020830

ABSTRACT

BACKGROUND: Extracorporeal shock wave therapy (ESWT) is mainly applied in tendon as well as bone problems based on stem-cell activation and healing acceleration. The effect of ESWT on muscle tissue is much less understood to date. However, from a clinical perspective, muscle injuries are of distinct interest especially in elite athletes such as soccer players. MATERIAL AND METHODS: A total of 26 rats were randomized into two groups. Group A received a single application of high-energetic focused ESWT (0.3 mJ/mm(2), 4 Hz, 1000 impulses, 10 J), whereas group B underwent the same procedure every 10 min for three sessions (3 × 0.3 mJ/mm(2), 4 Hz, 3 × 1000 impulses, totaling 30 J). Blood flow at a depth of 8 mm was measured continuously and noninvasively by a combined Laser-Doppler-Imaging and photospectrometric technique (Oxygen-to-see, O2C, LEA Medizintechnik, Germany). RESULTS: One minute after the application of high-energy ESWT blood flow in group A increased by 16.5% (P = 0.007). Thereafter, it decreased from minute 2 after application and remained significantly unchanged to baseline value until the end of the measuring period at 50 min (P = 0.550). Group B showed a similar significant increase in blood flow of 16.4% (P = 0.049) and a decrease afterward, too. After the second focused ESWT blood flow was boosted to 26.6% (P = 0.004), remaining significantly elevated until the third application was initiated. Muscular blood flow was increased to 29.8% after the third focused ESWT (P < 0.001), remaining significantly increased for another 10 min. CONCLUSIONS: Focused ESWT enhances blood flow in the muscle of rats. Moreover, repetitive ESWT extended this beneficial effect.


Subject(s)
High-Energy Shock Waves/therapeutic use , Microcirculation , Muscles/blood supply , Animals , Random Allocation , Rats, Sprague-Dawley
9.
Microvasc Res ; 104: 55-62, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26655582

ABSTRACT

BACKGROUND: Cold atmospheric plasma (CAP) has proven its benefits in the reduction of various bacteria and fungi in both in vitro and in vivo studies. Moreover, CAP generated by dielectric barrier discharge (DBD) promoted wound healing in vivo. Charged particles, chemically reactive species (such as O3, OH, H2O2, O, NxOy), ultraviolet radiation (UV-A and UV-B), strong oscillating electric fields as well as weak electric currents are produced by DBD operated in air. However, wound healing is a complex process, depending on nutrient and oxygen supply via cutaneous blood circulation. Therefore, this study examined the effects of CAP on cutaneous microcirculation in a prospective cohort setting. HYPOTHESIS: Cold atmospheric plasma application enhances cutaneous microcirculation. METHODS: Microcirculatory data of 20 healthy subjects (11 males, 9 females; mean age 35.2 ± 13.8 years; BMI 24.3 ± 3.1 kg/m(2)) were recorded continuously at a defined skin area at the radial forearm. Under standardized conditions, microcirculatory measurements were performed using a combined laser Doppler and photospectrometry system. After baseline measurement, CAP was applied by a DBD plasma device for 90 s to the same defined skin area of 22.5 cm(2). Immediately after the application cutaneous microcirculation was assessed for 30 min at the same site. RESULTS: After CAP application, tissue oxygen saturation immediately increased by 24% (63.8 ± 13.8% from 51.4 ± 13.2% at baseline, p<0.001) and stayed significantly elevated for 8 min. Cutaneous blood flow increased by 73% (41.0 ± 31.2 AU from 23.7 ± 20.8 AU at baseline, p<0.001) and remained upregulated for 11 min. Furthermore, cutaneous blood flow showed two peaks at 14 (29.8 ± 25.0 AU, p=0.049) and 19 min (29.8 ± 22.6 AU, p=0.048) after treatment. Postcapillary venous filling pressure continuously increased, but showed no significant change vs. baseline in the non-specific BMI group. Subgroup analysis revealed that tissue oxygen saturation, postcapillary venous filling pressure and blood flow increased more in case of a lower BMI. CONCLUSION: CAP increases cutaneous tissue oxygen saturation and capillary blood flow at the radial forearm of healthy volunteers. These results support recently published data on wound healing after CAP treatment. However, further studies are needed to determine if this treatment can improve the reduced microcirculation in diabetic foot ulcers. Moreover, repetitive application protocols have to be compared with a single session treatment approach.


Subject(s)
Microcirculation/physiology , Plasma Gases/pharmacology , Skin/blood supply , Adult , Cohort Studies , Female , Humans , Male , Middle Aged , Oxygen/metabolism , Prospective Studies , Regional Blood Flow , Wound Healing , Young Adult
10.
Medicine (Baltimore) ; 94(41): e1764, 2015 Oct.
Article in English | MEDLINE | ID: mdl-26469916

ABSTRACT

The regrowth of amputated digit tips represents a unique regenerative healing in mammals with subcutaneous volume regrowth, restoration of dactylogram, and suppression of scar formation. Although factor analysis in amphibians and even in mice is easy to obtain, safety of harvesting biomaterial from human digit tip amputations for analysis has not yet been described.The aim of this study was to evaluate if recovering wound exudate does hamper clinical outcome or influence microbiologic or inflammation status.A predefined cohort of 18 patients with fresh digit tip amputations was randomly assigned to receive standard therapy (debridement, occlusive dressing) with (n = 9) or without (n = 9) collection of the whole wound exudate in every dressing change. Primary endpoint (lengthening) and secondary endpoints (regeneration of dactylogram, nail bed and bone healing, time to complete wound closure, scar formation, 2-point discrimination, microbiologic analysis, inflammatory factors interleukin (IL)-1α, tumor necrosis factor-α, IL-4, and IL-6) were determined by an independent, blinded observer.Patients' characteristics showed no significant differences between the groups. All patients completed the study to the end of 3 months follow-up. Exudate collection did not influence primary and secondary endpoints. Furthermore, positive microbiologic findings as well as pus- and necrosis-like appearance neither impaired tissue restoration nor influenced inflammatory factor release.Here, the authors developed an easy and safe protocol for harvesting wound exudate from human digit tip amputations. For the first time, it was shown that harvesting does not impair regenerative healing. Using this method, further studies can be conducted to analyze regeneration associated factors in the human digit tip.DRKS.de Identifier: DRKS00006882 (UTN: U1111-1166-5723).


Subject(s)
Amputation, Traumatic , Exudates and Transudates , Finger Injuries , Wound Healing/physiology , Adult , Debridement , Enzyme-Linked Immunosorbent Assay , Female , Humans , Male , Occlusive Dressings , Prospective Studies , Regeneration , Treatment Outcome
11.
J Tissue Viability ; 24(4): 140-5, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26299636

ABSTRACT

BACKGROUND: Extracorporeal shock wave treatment (ESWT) has proven its clinical benefits in different fields of medicine. Tissue regeneration and healing is improved after shock wave treatment. Even in the case of burn wounds angiogenesis and re-epithelialization is accelerated, but ESWT in extensive burn wounds is impracticable. HYPOTHESIS: High energy ESWT influences cutaneous microcirculation at body regions remote from application site. METHODS: Eighteen Sprague Dawley rats were randomly assigned to two groups and received either high energy ESWT (Group A: total 1000 impulses, 10 J) or placebo shock wave treatment (Group B: 0 impulses, 0 J), applied to the dorsal lower leg of the hind limb. Ten minutes later microcirculatory effects were assessed at the contralateral lower leg of the hind limb (remote body region) by combined Laser-Doppler-Imaging and Photospectrometry. RESULTS: In Group A cutaneous capillary blood velocity was significantly increased by 152.8% vs. placebo ESWT at the remote body location (p = 0.01). Postcapillary venous filling pressure remained statistically unchanged (p > 0.05), while cutaneous tissue oxygen saturation increased by 12.7% in Group A (p = 0.220). CONCLUSION: High energy ESWT affects cutaneous hemodynamics in body regions remote from application site in a standard rat model. The results of this preliminary study indicate that ESWT might be beneficial even in disseminated and extensive burn wounds by remote shock wave effects and should therefore be subject to further scientific evaluation.


Subject(s)
Blood Flow Velocity/radiation effects , High-Energy Shock Waves , Microcirculation/radiation effects , Skin/blood supply , Skin/radiation effects , Animals , Burns/radiotherapy , Hindlimb , Humans , Laser-Doppler Flowmetry , Rats , Rats, Sprague-Dawley , Re-Epithelialization/radiation effects , Wound Healing/radiation effects
12.
Medicine (Baltimore) ; 94(27): e1104, 2015 Jul.
Article in English | MEDLINE | ID: mdl-26166102

ABSTRACT

Monopolar electrocautery is a fast and elegant cutting option. However, as it creates surgical smoke containing polycyclic aromatic hydrocarbons (PAHs), it may be hazardous to the health of the surgical team. Although new technologies, such as feedback mode (FM) and Teflon-coated blades (TBs), reduce tissue damage, their impact on surgical smoke creation has not yet been elucidated. Therefore, we analyzed the plume at its source.The aim of this study was to evaluate if electrocautery FM and TBs create less surgical smoke.Porcine tissue containing skin was cut in a standardized manner using sharp-edged Teflon-coated blades (SETBs), normal-shaped TBs, or stainless steel blades (SSBs). Experiments were performed using FM and pure-cut mode. Surgical smoke was sucked through filters or adsorption tubes. Subsequently, filters were scanned and analyzed using a spectrophotometer. A high-performance liquid chromatography (HPLC-UV) was performed to detect benzo[a]pyrene (BaP) and phenanthrene as 2 of the most critical PAHs. Temperature changes at the cutting site were measured by an infrared thermometer.In FM, more surgical smoke was created using SSB compared with TBs (P < 0.001). Furthermore, differences between FM and pure-cut mode were found for SSB and TB (P < 0.001), but not for SETB (P = 0.911). Photometric analysis revealed differences in the peak heights of the PAH spectrum. In HLPC-UV, the amount of BaP and phenanthrene detected was lower for TB compared with SSB. Tissue temperature variations increased when SSB was used in FM and pure-cut mode. Furthermore, different modes revealed higher temperature variations with the use of SETB (P = 0.004) and TB (P = 0.005) during cutting, but not SSB (P = 0.789).We found that the use of both TBs and FM was associated with reduced amounts of surgical smoke created during cutting. Thus, the surgical team may benefit from the adoption of such new technologies, which could contribute to the primary prevention of smoke-related diseases.


Subject(s)
Electrocoagulation/instrumentation , Polytetrafluoroethylene , Smoke/analysis , Smoke/prevention & control , Surgical Procedures, Operative/methods , Animals , Benzo(a)pyrene/analysis , Chromatography, High Pressure Liquid , Environmental Monitoring , Phenanthrenes/analysis , Swine , Temperature
13.
Pediatr Surg Int ; 31(4): 397-401, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25724865

ABSTRACT

PURPOSE: Hand burns are common in the pediatric population. Optimal hand function is a crucial component of a high-quality survival after burn injury. This can only be achieved with a coordinated approach to the injuries. The aim of this study was to review the management algorithm and outcomes of pediatric hand burns at our institution. METHODS: In total, 70 children fulfilling our study criteria were treated for a burn hand injury in our Burn Care Center between January 2008 and May 2013. RESULTS: 14 of the 70 pediatric patients underwent surgery because of the depth of the hand burns. The management algorithm depending on the depth of the burn is described. Two patients underwent correction surgery due to burn contractures later. CONCLUSION: For a successful outcome of the burned hand, the interdisciplinary involvement and cooperation of the plastic and pediatric surgeon, hand therapist, burn team, patient and their parents are crucial.


Subject(s)
Burns/surgery , Disease Management , Hand Injuries/surgery , Plastic Surgery Procedures/methods , Adolescent , Child , Child, Preschool , Female , Humans , Infant , Male , Retrospective Studies , Treatment Outcome
14.
J Reconstr Microsurg ; 30(8): 561-8, 2014 Oct.
Article in English | MEDLINE | ID: mdl-25184617

ABSTRACT

BACKGROUND: Long-term follow-up data of digital nerve reconstructions with nerve conduits are limited. Furthermore, it is not known whether nerve regeneration after tubulization is terminated after 12 months, or whether improvement can be expected after this period of time. Therefore, we present the long-term follow-up of two prospective clinical trials. PATIENTS AND METHODS: We invited 45 patients who were enrolled in two prospective clinical trials for long-term follow-up. All patients underwent digital nerve reconstruction with conduits made from bovine collagen I due to a gap length of < 26 mm. Sensibility was assessed using static and moving two-point discrimination and monofilament testing. Follow-up data of 1 week, 3, 6, and 12 months, and the current examination were available. Improvement of sensibility was investigated by comparison of the American Society for Surgery of the Hand classification score at 12-month follow-up with the score raised at current examination. RESULTS: We examined 20 reconstructed nerves in 16 patients with a mean follow-up of 58.1 months (range, 29.3-93.3 months). We found an improved sensibility at current follow-up compared with the 12-month follow-up in 13 cases. Three cases had the same values whereas four cases had worsened sensibility. Improvement of sensibility was associated with a significantly shorter nerve gap length with significantly better results if the gap length was < 10 mm. CONCLUSION: Our results provide evidence that the long-term recovery of sensibility after digital nerve tubulization depends on the nerve gap length with better results in those < 10 mm. Nerve regeneration after tubulization seems not to be terminated after 12 months.


Subject(s)
Guided Tissue Regeneration , Hand Injuries/surgery , Hand/innervation , Peripheral Nerve Injuries/surgery , Plastic Surgery Procedures , Absorbable Implants , Adult , Aged , Biocompatible Materials , Collagen Type I , Female , Follow-Up Studies , Hand/surgery , Hand Injuries/complications , Hand Injuries/physiopathology , Humans , Male , Middle Aged , Nerve Regeneration , Peripheral Nerve Injuries/etiology , Peripheral Nerve Injuries/physiopathology , Prospective Studies , Recovery of Function , Time Factors , Treatment Outcome
15.
Burns ; 40(8): 1738-42, 2014 Dec.
Article in English | MEDLINE | ID: mdl-24986594

ABSTRACT

OBJECTIVE: Obesity is an important predictor of mortality and morbidity during a hospital stay. There is very little data concerning the impact of the BMI on clinical outcomes in obese burn patients. The purpose of this study is to document the general epidemiological aspects of thermal injuries in an obese population and draw attention to topics relating to the management, rehabilitation and prognosis of burns in this emerging subpopulation of patients. METHODS: All patients >16 years of age admitted to the burn unit between January 2008 and December 2012 and fulfilling the burn center referral criteria were enrolled in the study. SPSS version 20 (SPSS GmbH Software, Illinois, USA) was employed for data analysis. RESULTS: Eleven extreme obese patients (men:women, 6:5) had a mean BMI of 38kg/m(2). Their incidence in our study was 5.5%. The mean length of stay was 41.5 days, almost twice that of the non-obese. The presence of co-morbidities such as diabetes, hypertension, cardiac disease, or pulmonary disease, the problematic wound healing and the burn wound infection were significantly higher in the obese patients than in the non-obese. The mortality of obese burned patients was 36.4%. CONCLUSIONS: These facts indicate admission of these patients to a burn care unit for the best possible treatment although they might not always fulfill criteria for admission to burn intensive care unit. Burn centers must be also prepared in terms of special nursing equipment for obese patients.


Subject(s)
Burn Units/statistics & numerical data , Burns/epidemiology , Obesity/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Analysis of Variance , Body Mass Index , Burns/rehabilitation , Burns/therapy , Comorbidity , Female , Humans , Incidence , Length of Stay/statistics & numerical data , Male , Middle Aged , Prognosis , Retrospective Studies , Risk Factors , Wound Infection/epidemiology , Young Adult
16.
Burns ; 40(8): 1476-80, 2014 Dec.
Article in English | MEDLINE | ID: mdl-24630819

ABSTRACT

OBJECTIVE: Inhalation injury is suspected in patients with facial and neck burn-injuries and in patients who suffered burns in an enclosed space. Inhalation injury is associated with a disappointingly high morbidity and mortality in spite of advances in diagnostics and therapy.Prophylactic antibiotic therapy in patients with diagnosed inhalation injury is still a controversial subject.The epidemiologic characteristics of the burn patients with diagnosed inhalation injury in our clinic receiving prophylactic antibiotic therapy and mortality of these patients will be referred in this study. METHODS: Patients >16 years of age admitted to the burn unit between January 2008 and December 2012 and fulfilling the burn center referral criteria according the German Burn Association were enrolled in the study. RESULTS: 58 patients (male:female 47:11) were diagnosed with an inhalation injury by their admission. The average length of hospital stay was 27.5 days, whereas of the patients with no inhalation injury was 16 days (p=0.04). 56.9% of the patients underwent tracheostomy. An escalation of the antibiotic therapy was done in 39.7% of the patients with inhalation injury and in 20.3% of the patients without one. The mortality of inhalation injury patients was 12.1%. CONCLUSIONS: The development of pneumonia is not influenced in a statistical significant way by the use of prophylactic antibiotics. We do recommend the administration of prophylactic antibiotic therapy to patients with diagnosed inhalation trauma, as the mortality of these patients was lower in comparison to other studies.


Subject(s)
Anti-Bacterial Agents/therapeutic use , Burns, Inhalation/therapy , Penicillanic Acid/analogs & derivatives , Pneumonia, Bacterial/prevention & control , Respiration, Artificial , Adolescent , Adult , Aged , Burn Units , Burns/complications , Burns/therapy , Burns, Inhalation/complications , Burns, Inhalation/diagnosis , Case-Control Studies , Female , Humans , Length of Stay , Male , Middle Aged , Penicillanic Acid/therapeutic use , Piperacillin/therapeutic use , Piperacillin, Tazobactam Drug Combination , Pneumonia, Bacterial/complications , Retrospective Studies , Tracheostomy , Young Adult
17.
J Reconstr Microsurg ; 29(8): 517-22, 2013 Oct.
Article in English | MEDLINE | ID: mdl-23818251

ABSTRACT

Nerve conduits are nonneural, hollow tubular structures designed to bridge the gap of a sectioned nerve, to protect the nerve from scar formation, and to guide the regenerating fibers into the distal nerve stump. In the 8-year experience of our department, four patients aged 14 to 50 years had an unsuccessful implantation of a nerve conduit (NeuraGen, Integra, Plainsboro, NJ). In these four patients, the collagen tubes were replaced by an autogenous nerve graft. The histological specimens showed characteristic histological findings of a scar neuroma without any signs of foreign body reaction in three cases and with minimal foreign body reaction in one case. The collagen nerve tube was completely resorbed in all cases after a time period of 6 to 17 months and could not be detected marco- or microscopically.To our knowledge, this is the first report in the English and German literature describing the histological characteristics of explanted collagen nerve tubes in humans.


Subject(s)
Absorbable Implants , Collagen/therapeutic use , Finger Injuries/surgery , Neurosurgical Procedures/methods , Peripheral Nerve Injuries/surgery , Adolescent , Adult , Female , Humans , Male , Middle Aged , Nerve Transfer/methods , Treatment Failure
18.
J Med Case Rep ; 7: 22, 2013 Jan 15.
Article in English | MEDLINE | ID: mdl-23320897

ABSTRACT

INTRODUCTION: Blunt cardiac rupture is an exceedingly rare injury. CASE PRESENTATION: We report a case of blunt cardiac trauma in a 43-year-old Caucasian German mother with pectus excavatum who presented after a car accident in which she had been sitting in the front seat holding her two-year-old boy in her arms. The mother was awake and alert during the initial two hours after the accident but then proceeded to hemodynamically collapse. The child did not sustain any severe injuries. Intraoperatively, a combined one-cm laceration of the left atrium and right ventricle was found. CONCLUSION: Patients with pectus excavatum have an increased risk for cardiac rupture after blunt chest trauma because of compression between the sternum and spine. Therefore, patients with pectus excavatum and blunt chest trauma should be admitted to a Level I Trauma Center with a high degree of suspicion.

19.
Breast ; 22(1): 74-7, 2013 Feb.
Article in English | MEDLINE | ID: mdl-22726991

ABSTRACT

Nipple-areola complex (NAC) reconstruction tends to be the final phase of post-mastectomy reconstruction for many cancer patients, as it transforms the amorphous breast mound into a more aesthetically realistic breast. A variety of local-flap based techniques have been reported. In this paper we will describe a cantral-pedicled intracorial skin flap technique. Review of 12 patients showed aesthetic pleasing NAC and durable long-term results of nipple projection.


Subject(s)
Breast Neoplasms/surgery , Mammaplasty/methods , Nipples/surgery , Surgical Flaps , Adult , Female , Humans , Mastectomy , Middle Aged , Treatment Outcome
20.
Eplasty ; 12: e33, 2012.
Article in English | MEDLINE | ID: mdl-22848777

ABSTRACT

In case of blast injuries, traumatic tattoos can result from accidental inclusions of intradermal pigmented particles. To avoid these tattoos, especially in esthetical areas like the head and neck region and the hands, the primary goal in our treatment is to remove all particles and foreign bodies. Superficial foreign bodies can easily be removed by brushes or dermabrasion. Deeper lesions are a challenge for plastic surgeons, because they are not so easily removed. Ablation by a water jet surgical tool, the Versajet-system (Smith & Nephew Inc, Andover, MA), enables the removal of nearly all particles and foreign bodies, which sustained a blast injury of the face or the hands. Aim of this paper is to describe the method of using this hydrosurgery system in blast injuries in esthetical zones and its advantages by presenting cases of two patients of us.

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