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Laryngorhinootologie ; 81(10): 725-31, 2002 Oct.
Article in German | MEDLINE | ID: mdl-12397523

ABSTRACT

Postoperative nausea and vomiting (PONV) are among the most common complications in operative medicine. Especially patients undergoing middle ear surgery or adenotonsillectomy are frequently associated with PONV (70 %). Furthermore, emesis carries the risk of severe postoperative complications and is associated with additional costs and distress in patient management. If the patient carries a high risk for postoperative emesis, the patient should receive a prophylactic antiemetic therapy. 5-HT 3 receptor antagonists are highly effective in prevention and management of PONV. This review will discuss pathophysiology, prophylaxis and treatment of postoperative nausea and vomiting after E.N.T. surgery.


Subject(s)
Antiemetics/administration & dosage , Otorhinolaryngologic Diseases/surgery , Postoperative Nausea and Vomiting/prevention & control , Receptors, Serotonin/drug effects , Serotonin Antagonists/administration & dosage , Anesthetics/adverse effects , Antiemetics/adverse effects , Autonomic Nervous System/physiopathology , Humans , Postoperative Nausea and Vomiting/physiopathology , Premedication , Receptors, Serotonin/physiology , Receptors, Serotonin, 5-HT3 , Risk Factors , Serotonin Antagonists/adverse effects
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