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2.
J Clin Med ; 7(2)2018 Feb 12.
Article in English | MEDLINE | ID: mdl-29439542

ABSTRACT

Non-surgical left atrial appendage occlusion has emerged as an alternative to anticoagulant therapy in the management of stroke risk in patients with atrial fibrillation. This review reports on some of the more common devices that are currently being used to manage patients in this challenging group.

3.
Pacing Clin Electrophysiol ; 39(10): 1046-1051, 2016 Oct.
Article in English | MEDLINE | ID: mdl-27530209

ABSTRACT

BACKGROUND: Implantable cardioverter defibrillator (ICD) implantation is being performed differently at many hospitals, with some keeping patients overnight after procedure while others discharge patients home same day. In addition, many centers are now performing ICD surgery while on warfarin anticoagulation. There are, however, limited data on outpatient ICD surgery on anticoagulated (AC) patients. OBJECTIVE: We wished to evaluate the safety of performing outpatient ICD surgery with and without warfarin anticoagulation. METHODS: We evaluated 866 patients who underwent outpatient ICD surgery between April 2010 and September 2014. Patients who were on novel oral anticoagulants, or did not have an international normalized ratio drawn within 24 hours of the procedure were excluded and the remainder were divided into two groups based on whether they were on (n = 230) or off (n = 518) warfarin anticoagulation. We evaluated both procedural and 30-day complications in both groups. RESULTS: The complication rate at 30 days in the warfarin AC group was 4.3%, while in the nonanticoagulated (NAC) group was 2.9% and not significantly different (P = 0.31). However, the pocket hematoma rate in the warfarin anticoagulated group was 3.5%, as compared to the NAC group that was 0.4% (P = 0.001). CONCLUSION: Complications from ICD surgery are low in the ambulatory setting on or off warfarin anticoagulation and appear to be comparable. However, warfarin use during ICD surgery is associated with an increased risk of pocket hematoma.


Subject(s)
Ambulatory Care , Anticoagulants/adverse effects , Defibrillators, Implantable/adverse effects , Warfarin/adverse effects , Aged , Female , Hematoma/chemically induced , Humans , Male , Postoperative Complications , Prosthesis Implantation/adverse effects , Safety
4.
Pacing Clin Electrophysiol ; 36(5): 541-6, 2013 May.
Article in English | MEDLINE | ID: mdl-23437781

ABSTRACT

BACKGROUND: Progress in implantable cardiac defibrillator (ICD) technology has allowed for switching the sensing polarity for the detection of ventricular fibrillation (VF). However, whether one sensing polarity confers additional advantage over the other is not known. OBJECTIVES: To determine whether one sensing polarity is superior to the other for the detection of VF. METHODS: Patients were enrolled into a prospective randomized study of sensing of VF and R waves in normal rhythm. Sensing of VF was determined by number of under sensed beats (USB), and time to detection of VF (TDVF). Each patient underwent ICD implantation followed by testing of the ICD. At each induction, patients were randomized to sensing in extended bipolar (EBP) or true bipolar (TBP) configuration. Additionally, R waves were compared at implant and at 1-month follow-up. RESULTS: A total of 50 patients were enrolled into the study. When evaluating the primary endpoint, no difference was found between USB in EBP or TBP configuration; 1.1 ± 1.2 beats versus 1.3 ± 1.3 beats; P = NS. Also, no difference was found between TDVF in EBP or TBP configurations; 5.9 ± 0.6 seconds versus 5.9 ± 0.6 seconds; P = NS. With regard to the secondary endpoints, there was no difference between R waves in EBP or TBP configurations at the time of implant 10.9 ± 4.8 mV versus 10.9 ± 4.8 mV P = NS; or at 1-month follow-up 12.4 ± 4.7 mV versus 12.0 ± 5.4 mV P = NS. CONCLUSIONS: There is no difference in the detection of VF between EBP or TBP configurations in patients undergoing ICD implantation.


Subject(s)
Defibrillators, Implantable , Diagnosis, Computer-Assisted/methods , Electrocardiography, Ambulatory/instrumentation , Electrocardiography, Ambulatory/methods , Ventricular Fibrillation/diagnosis , Ventricular Fibrillation/prevention & control , Algorithms , Female , Humans , Male , Middle Aged , Prospective Studies , Reproducibility of Results , Sensitivity and Specificity , Treatment Outcome
5.
Europace ; 12(6): 903-4, 2010 Jun.
Article in English | MEDLINE | ID: mdl-20118489

ABSTRACT

An athletic 43-year-old man presented with symptomatic bradycardia and atrial flutter after being diagnosed with HLA B27 associated spondyloarthropathy several months earlier. The patient was admitted and underwent electrophysiology evaluation with ablation of his atrial flutter and eventually underwent pacemaker implantation. His cardiac workup showed a structurally normal heart and strongly suggested that his HLA B27 associated spondyloarthropathy was responsible for his presentation. A review of the literature suggests that HLA B27 spondyloarthropathy related heart block may be an often overlooked cause of heart block in otherwise healthy patients.


Subject(s)
Atrial Flutter/etiology , HLA-B27 Antigen/immunology , Heart Block/etiology , Spondylarthropathies/complications , Spondylarthropathies/immunology , Adult , Atrial Flutter/diagnosis , Atrial Flutter/therapy , Cardiac Pacing, Artificial , Electrocardiography , Heart Block/diagnosis , Heart Block/therapy , Humans , Male
6.
Med Sci Monit ; 9(3): PI19-23, 2003 Mar.
Article in English | MEDLINE | ID: mdl-12640352

ABSTRACT

BACKGROUND: It is unclear whether acute conversion of atrial fibrillation (AF) with anti-arrhythmic drugs following cardiac surgery restores and/or maintains sinus rhythm or reduces hospital length of stay (LOS). MATERIAL/METHODS: A randomized prospective pilot study was conducted in 2 teaching hospitals from 3/28/98 to 8/2/99 to study the effect of the early use of ibutilide or propafenone on the duration of AF, rhythm at discharge, and LOS. A total of 42 stable patients with new AF after surgery were randomized to oral propafenone (600mg, single dose; n=20), ibutilide (1 mg up to 2 doses if necessary; n=10), or rate control only (n=12). Agents used for rate control were left to the discretion of the primary physician but beta-blockers were encouraged. RESULTS: Pre-randomization distribution of diabetes, CHF, previous AF, and the use of beta-blockers were similar in all groups. At 24 hours 0%, 65% and 34% of patients in the ibutilide (p=0.01), propafenone (p=ns), and rate control groups respectively remained in AF. Although ibutilide decreased AF duration, recurrence rates were 90%, 41%, and 58% in those groups (p=ns compared to rate control). Of the 3 patients who did not convert, all received propafenone. There was no difference in LOS or rhythm at discharge. CONCLUSIONS: Ibutilide but not propafenone decreases the duration of AF after cardiac surgery and neither appears to affect LOS or rhythm at discharge. This data suggests that post operative AF is transient and routine anti-arrhythmic therapy is not necessary for the majority of patients.


Subject(s)
Anti-Arrhythmia Agents/therapeutic use , Atrial Fibrillation/drug therapy , Atrial Fibrillation/etiology , Cardiac Surgical Procedures/adverse effects , Postoperative Complications/drug therapy , Postoperative Complications/etiology , Propafenone/therapeutic use , Sulfonamides/therapeutic use , Adrenergic beta-Antagonists/therapeutic use , Aged , Female , Humans , Length of Stay , Male , Middle Aged , Prospective Studies
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