[The protective activity of preparations made from the tick-borne encephalitis virus grown using different cell cultures]. / Izuchenie protektivnoi aktivnosti preparatov iz virusa kleshchevogo éntsefalita, vyrashchennogo s ispol'zovaniem razlichnykh kletochnykh kul'tur.

The preparations of tick-borne encephalitis (TBE) virus grown in swine embryo kidney cell culture have been shown to possess pronounced protective activity per unit of virion protein E in comparison with TBE virus preparations derived from cell culture 4647 and chick embryo cell culture. The antigenic activity of all virus preparations under study has proved to be practically the same. The role of post-translation modifications of TBE virus protein E in the manifestation of some of its biological properties is discussed.

[Immunity indices of mice immunized with different vaccines against Japanese encephalitis]. / Pokazateli immuniteta u myshei, immunizirovannykh razlichnymi vaktsinami protiv iaponskogo éntsefalita.

The test of adoptive transfer of immunity demonstrated that in the mice vaccinated with inactivated Japanese encephalitis vaccines the protective activity to the homologous virus is provided predominantly by B-lymphocytes the protective effect of which is enhanced by cooperative interaction with T-lymphocytes. The culture (CV) and purified brain (BV) vaccines induce high levels of humoral and cell-mediated immunity, however, the capacity of CV to produce antibody is higher than that of BV. Both preparations do not cause in vaccinated mice any changes in responsiveness to extraneous antigen (sheep red cells), or disorders in chemotaxic mobility of leukocytes and phagocytic activity of macrophages.