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Bull Exp Biol Med ; 139(3): 331-3, 2005 Mar.
Article in English, Russian | MEDLINE | ID: mdl-16027845

ABSTRACT

Naloxone hydrochloride, an opioid receptors blocker, was administered to chick embryos. Morphological analysis of femoral bones of embryos showed an appreciable increase in the thickness of the perichondral bone cuff in the tubular bone diaphyses and increased mitotic activity in the zone of proliferating young cartilage of the epiphyseal plate.


Subject(s)
Bone and Bones/embryology , Naloxone/pharmacology , Osteogenesis/drug effects , Animals , Bone and Bones/cytology , Cell Proliferation/drug effects , Chick Embryo , Growth Plate/cytology , Growth Plate/drug effects , Mitosis/drug effects , Osteocytes/drug effects , Time Factors
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