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Am J Med Sci ; 321(2): 152-5, 2001 Feb.
Article in English | MEDLINE | ID: mdl-11271750

ABSTRACT

Aortic valve abscesses (AVAs) are a devastating complication of aortic valve endocarditis. Over 8 years, 25 patients were diagnosed with AVA by transesophageal echo (TEE). Management and outcomes were then analyzed. Eleven (44%) AVAs involved prosthetic valves, and 6 (24%) occurred in congenitally malformed valves. Twenty patients (80%) underwent surgical intervention; the rest were treated medically. Eleven (44%) of the patients died [6 (30%) surgery patients and all the medical patients]. Eight of 11 (73%) patients who died were culture positive for Staphylococcus aureus. All patients with congenitally malformed aortic valves underwent surgical intervention and survived. We conclude that: (1) despite advances in therapy and diagnosis, patients with AVAs have a high mortality rate; (2) prognosis with AVA is especially poor when S aureus is the infectious organism; (3) patients with AVAs in congenitally malformed valves have a great outcome with surgery; (4) patients treated medically have a very poor prognosis; earlier identification by TEE may be critical to improving survival.


Subject(s)
Abscess/diagnostic imaging , Aortic Valve Insufficiency/diagnostic imaging , Echocardiography, Transesophageal , Endocarditis, Bacterial/diagnostic imaging , Staphylococcal Infections/diagnostic imaging , Abscess/drug therapy , Abscess/mortality , Abscess/surgery , Adult , Aged , Anti-Bacterial Agents/therapeutic use , Antifungal Agents/therapeutic use , Aortic Valve/abnormalities , Aortic Valve Insufficiency/drug therapy , Aortic Valve Insufficiency/etiology , Aortic Valve Insufficiency/mortality , Aortic Valve Insufficiency/surgery , Candidiasis/diagnostic imaging , Combined Modality Therapy , Disease Susceptibility , Embolism/etiology , Endocarditis, Bacterial/drug therapy , Endocarditis, Bacterial/mortality , Endocarditis, Bacterial/surgery , Female , Heart Block/etiology , Heart Valve Prosthesis Implantation , Humans , Male , Middle Aged , Multiple Organ Failure/etiology , Multiple Organ Failure/mortality , Prosthesis-Related Infections/diagnostic imaging , Prosthesis-Related Infections/drug therapy , Prosthesis-Related Infections/mortality , Prosthesis-Related Infections/surgery , Staphylococcal Infections/drug therapy , Staphylococcal Infections/mortality , Staphylococcal Infections/surgery , Streptococcal Infections/diagnostic imaging , Streptococcal Infections/drug therapy , Streptococcal Infections/mortality , Streptococcal Infections/surgery , Treatment Outcome
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