A Modern Approach to Treat Molar/Incisor Pattern Periodontitis-Review.

Molar-incisor pattern periodontitis (MIPP) is a severe form of periodontal disease characterized by rapid attachment loss and bone destruction affecting the molars and incisors. Formerly referred to as aggressive periodontitis, the terminology for this condition was revised after the 2017 workshop on the classification of periodontal and peri-implant diseases and conditions. Despite the modification in nomenclature, the treatment strategies for MIPP remain a critical area of investigation. The core principles of MIPP treatment involve controlling local and systemic risk factors, managing inflammation, and arresting disease progression. Traditional non-surgical periodontal therapy, including scaling and root planing, is commonly employed as an initial step together with the prescription of antibiotics. Surgical intervention may be necessary to address the severe attachment loss. Surgical techniques like resective and regenerative procedures can aid in achieving periodontal health and improving esthetic outcomes. This review article aims to provide an overview of the current understanding and advancements in the treatment modalities of MIPP. Through an extensive analysis of the existing literature, we discuss various modern therapeutic approaches that have been explored for managing this challenging periodontal condition.

Childhood Obesity, Genetic Variation, and Dental Age.

Purpose: The purpose of this study was to determine if dental ages are more advanced in overweight children and influenced by genetic variation. Methods: Panoramic radiographs from 577 children were obtained. For performing genetic studies, an additional 236 subjects had panoramic radiographs and whole saliva samples collected. Genotyping of IGF, FGF, and FGFR markers was done. Dental age was determined in 177 patients utilizing Demerjian's method and panoramic radiographs. Skeletal maturation was determined in 28 patients using Baccetti's cervical vertebral maturation method on lateral cephalograms. PLINK was used to test for over-representation of alleles. Results: FGF7, FGF10, and FGF13 were significantly associated with obesity (P = 0.02). When dental age was considered, overweight and obese children are more likely to have dental ages more advanced than their chronological ages (P = 0.05). An excess of heterozygotes of FGF18 rs4073716 was found in children with dental age more advanced than their chronological age (P=0.04). Conclusions: Overweight and obese children have dental ages more advanced than their chronological ages, and this occurrence may be influenced by genetic variation in FGF18.

Kidney disease, increased body mass indexes, and anterior teeth treatment needs

Objective: The purpose of this study was to test the hypothesis that individuals with kidney disease will have more dental issues affecting their anterior teeth. This effect on oral health would be independent from the effects of their higher frequency of obesity. Methods : Using the University of Pittsburgh School of Dental Medicine Dental Registry and DNA Repository project, anterior teeth treatment history was evaluated for patients with kidney disease. Four thousand nine hundred and eighty-three individuals were evaluated. Individuals with kidney disease were compared to individuals who did not present the condition. Results : One hundred and three individuals reported kidney disease and 1,424 had history of treatment of anterior teeth. Individuals with kidney disease had significant more anterior teeth treatments (p=0.001). Individuals who reported kidney disease also had a higher frequency of overweight individuals, but anterior teeth restoration needs were higher in all individuals with kidney disease, independent of their body mass index. Conclusion : Chronic kidney disease increases treatment needs of anterior teeth and potentially leads to worse oral health outcomes and warrants changes in protocols for treatment of individuals with chronic kidney disease.

Objetivo: O objetivo dessa série de avaliações foi testar a hipótese de que pessoas com doença renal têm mais necessidades de tratamento dos dentes anteriores. Esse efeito seria independente do risco aumentado de ser obeso. Métodos : Através do projeto da Faculdade de Odontologia da Universidade de Pittsburgh entitulado Dental Registry and DNA Repository , foi avaliada a história de tratamento em dentes anteriores em pacientes com doença renal. Quatro mil novecentos e oitenta e três indivíduos foram estudados. Resultados : Cento e três indivíduos reportaram ter doença renal e 1.424 pessoas tinham história de tratamento em dentes anteriores. Indivíduos com doença renal tiveram mais tratamento em dentes anteriores (p=0.001). Pessoas que reportaram doença renal também tiveram uma maior freqüência de obesidade, todavia necessidade de tratamento em dentes anteriores foi maior em indivíduos com doença renal, independente do índice de massa corporal. Conclusão : Doença renal crônica aumenta a necessidade de tratamrnto dos dentes anteriores, o que aumenta a chance de perda dentária e sugere que um protocol diferente para tartar pessoas com doença renal crônica seja uma medida justificada.