Central Line Associated Bloodstream Infections in Critical Ill Patients during and before the COVID-19 Pandemic.

(1) Background: The purpose of this study was to evaluate the impact of the COVID-19 pandemic on the rates of central line-associated bloodstream infections (CLABSI), its etiology, and risk factors in critically ill patients, because Slovakia was one of the countries experiencing a high burden of COVID-19 infections, and hospitals faced greater challenges in preventing and managing CLABSI; (2) Methods: A retrospective analysis of CLABSI data from all patients admitted to adult respiratory intensive care units before and during COVID-19 pandemic was conducted. We followed the guidelines of the Center for Disease Control surveillance methodology for CLABSI. Data were analyzed using STATISTICA 13.1; (3) Results: We analyzed the data of 803 ICU patients hospitalized for 8385 bed days, with 7803 central line days. Forty-five CLABSI events were identified. The CLABSI rate significantly increased during the COVID-19 pandemic compared to before the COVID-19 pandemic (2.81 versus 7.47 events per 1000 central line days, (p < 0.001). The most frequently identified pathogens causing CLABSI were Gram-negative organisms (60.20%). The risk factors found to increase the probability of developing CLABSI were length of stay (OR = 1.080; 95% Cl: 1.057-1.103; p < 0.001) and COVID-19 (OR = 5.485; 95% Cl: 32.706-11.116; p < 0.001). (4) Conclusions: The COVID-19 pandemic was associated with increases in CLABSI in ICUs. These data underscore the need to increase efforts in providing surveillance of CLABSI and implementing infection prevention measures.

World´s COVID-19 anti-pandemic measures in the context of postural and spine disorders in primary school children in Slovakia.

INTRODUCTION: This study was aimed to estimate the effect of one-year persistence of COVID-19 anti-pandemic measures on the posture and spine in children of younger school age in Slovakia. MATERIAL AND METHODS: A total of 135 children aged between 6 and 9 years participated in this study. The examination of posture and spine was carried out in 4 schools in 4 different districts in Slovakia. The posture was evaluated in February 2020, before anti-pandemic restrictions and in period from May 2021, after one year of anti-pandemic restrictions. Modified methodology according to Napoleon Wolanski was used to evaluate the posture. RESULTS: For the entire study group, the mean posture disorder level score before anti-pandemic restrictions was 5.667 (±1.75) and it rose to 7.844 (±0.64). Prevalence of posture disorders rose from 71.11 % to 91.3 % in the study group. The most affected segments were lumbar spine and pelvis, followed by deformities of the thoracis spinae. The mean pathology level score for entire group in these segments rose as followed: in the lumbar spine from 0.6 (±0.61) to 1.022 (±0.75); in the pelvis from 0.444 (±0.54) to 0.772 (±0.73) and in the thoracis spine from 0.378 (±0.53) to 0.578 (±0.61). CONCLUSION: Study confirmed a worsening of the posture and spine in school children after a one year of strict anti-pandemic measures. As postural changes increased by 20 % during the year, it seems necessary to implement appropriate preventives programs for children, which could have the potential to improve their postural state (Tab. 2, Fig. 1, Ref. 37). Text in PDF www.elis.sk Keywords: anti-pandemic restriction, e-learning, COVID-19, postural disorders, spine deformities.

Prediction of the Epidemiological Situation of Tuberculosis in Slovakia by 2040- Data Update.

BACKGROUND: Despite the available diagnostics and treatment, tuberculosis (TB) is a serious infectious disease currently occurring. Even some high-income countries in the world do not fully control it at this time. The reason for this situation is the lack of elimination programs to address the situation. The aim of the update of the prediction data was to create a presumption of TB development in Slovakia by 2040. METHODS: We used the time series prediction method with exponential equalization. The basis for the calculation were historical data on the incidence of TB from 1960 to 2018 in Slovakia (data for the last 58 yr). This time series has a clearly declining level. In view of this trend, we have set a threshold, whether and when the incidence in the future will fall below 5.0 patients per 100,000 inhabitants. RESULTS: In case of a favorable development, the limit of our incidence drop below 5.0 cases per 100 000 inhabitants in 2022, when the incidence will be 4.91 per 100 000 inhabitants. In 2040, the predicted incidence of TB should be 1.78 per 100 000 inhabitants. A gradual decline may also be related to a decrease in the population of the Slovak Republic. CONCLUSION: Slovakia belongs to those countries of the world where TB is under control. Increased surveillance of high-risk communities through community interventions and countries' readiness for global migration can help to influence factors that may aggravate the epidemiological situation of TB.