[Factors Related to Tympanic Membrane Perforation in Children with Acute Suppurative Otitis Media].

Objective To explore the factors related to tympanic membrane perforation in children with acute suppurative otitis media,and to provide reference for clinical practice. Methods We reviewed the clinical data of 1274 children with acute suppurative otitis media from February 2017 to May 2020,and analyzed the factors related to tympanic membrane perforation. Results Tympanic membrane perforation occurred in 67 out of the 1274 children with acute suppurative otitis media,with the incidence of 5.27%.The univariate analysis showed that 11 factors including the duration of onset(t=2.381,P=0.017),upper respiratory tract infection(χ2=12.228,P=0.000),pulmonary infection(χ2=5.242, P=0.022),chronic sinusitis(χ2=12.715,P=0.000),adenoid hypertrophy(χ2=4.783,P=0.029),tympanic empyema(χ2=16.020,P=0.000),the duration of using antibiotics(t=-2.277,P=0.025),combined use of antibiotics(χ2=5.587,P=0.018),the time from onset to selection of antibiotics according to drug sensitivity(t=3.716,P=0.000),procalcitonin(t=2.599,P=0.009),and white blood cell count in peripheral blood(t=2.196,P=0.031)were related to tympanic membrane perforation in children with acute suppurative otitis media.The multivariate logistic analysis showed that the duration of onset(OR=4.854,95% CI=2.675-8.806,P=0.000),upper respiratory tract infection(OR=6.506,95% CI=3.213-13.171,P=0.000),chronic sinusitis(OR=7.866,95% CI=3.780-16.370,P=0.000),tympanic empyema(OR=2.625,95% CI=1.442-4.777,P=0.002),and time from onset to selection of antibiotics according to drug sensitivity(OR=5.107,95% CI=2.129-12.248,P=0.000)were independent risk factors for tympanic membrane perforation in children with acute suppurative otitis media. Conclusion The incidence of tympanic membrane perforation in children with acute suppurative otitis media can be reduced by early treatment,keeping the Eustachian tube unobstructed,draining the tympanic cavity,preventing chronic sinusitis and upper respiratory tract infection,early drug sensitivity test,and selection of antibiotics based on the test results.

[Fast Removal of CT Ring Artifacts].

OBJECTIVE: To explore how to remove CT ring-shaped artifact quickly and effectively, and to improve accuracy of CT reconstruction image. METHODS: CT graphics (including the ring-shaped artifacts) were used first in coordinate transformation with a new transformation method. A two-dimensional filter was designed to filter the image. Then, a one-dimensional filter was used to re-filter the image. Finally, a new transform method was used to restore the image. RESULTS: The two-step coordinate transformation of ring-shaped artifact algorithm resulted in accurate restored original CT image, effectively reducing its interference on useful information. CONCLUSION: The method described in this study can overcome disadvantages of existing methods and obtain good results.

[Compatible biomass models for main tree species with measurement error in Heilongjiang Province of Northeast China].

Based on the biomass data of 516 sampling trees, and by using non-linear error-in-variable modeling approach, the compatible models for the total biomass and the biomass of six components including aboveground part, underground part, stem, crown, branch, and foliage of 15 major tree species (or groups) in Heilongjiang Province were established, and the best models for the total biomass and components biomass were selected. The compatible models based on total biomass were developed by adopting the method of joint control different level ratio function. The heteroscedasticity of the models for total biomass was eliminated with log transformation, and the weighted regression was applied to the models for each individual component. Among the compatible biomass models established for the 15 major species (or groups) , the model for total biomass had the highest prediction precision (90% or more), followed by the models for aboveground part and stem biomass, with a precision of 87.5% or more. The prediction precision of the biomass models for other components was relatively low, but it was still greater than 80% for most test tree species. The modeling efficiency (EF) values of the total, aboveground part, and stem biomass models for all the tree species (or groups) were over 0.9, and the EF values of the underground part, crown, branch, and foliage biomass models were over 0.8.

[Expression and its clinical significance of hsa-miR-155 in serum of endometrial cancer].

OBJECTIVE: to investigate the expression of the hsa-miR-155 in serum of endometrial cancer and its clinical significance. METHODS: collected 44 cases blood specimens before surgery operation from Sep. 2008 to Dec. 2009, and collected 12 cases blood specimens from the health of volunteers in comparison. Real time quantity PCR was used to detect the expression of hsa-miR-155 in those specimens and analyzed clinical pathological with the expression of hsa-mir-155 in endometrial cancer. RESULTS: the expression of hsa-miR-155 was (3.9 ± 0.7) in endometrial cancer, which was significantly higher than that in control group (P < 0.01). The expressions of hsa-miR-155 were (3.7 ± 0.6), (3.9 ± 0.6) and (3.7 ± 0.6) times in well, moderately and poorly differentiated endometrial cancer, respectively, while there were not significant difference (P > 0.05). The expressions were (3.8 ± 0.6) and (3.9 ± 0.6) times between endometrioid adenocarcinoma and non-endometrioid adenocarcinoma, and there were significant difference (P > 0.05). The expressions were (2.1 ± 0.4) and (5.6 ± 0.8) times in stage I - II and III - IV endometrial cancer, respectively, in which there were significant difference (P < 0.05). The expressions of hsa-miR-155 were (5.5 ± 0.5) and (1.9 ± 0.2) times between lymph node metastasis and without lymph node metastasis in endometrial cancer, in which there were significant difference (P < 0.01). CONCLUSION: Hsa-miR-155 may play an important role in the proliferation, and metastasis of endometrial cancer, which may be a indicator in the diagnosis and prognosis of endometrial cancer and may be used as a predictive biomarker.

[A clinical study of immediate dental implant and immediate restoration].

OBJECTIVE: To evaluate the clinical results of immediate implant and immediate restoration and to discuss the applying principles of these techniques. METHODS: Fourteen cases underwent immediate implant surgery for 37 dental implants immediately after the teeth or roots were extracted. Among them, 6 cases (14 implants) received immediate restoration after implant placement. The second stage operation and final restoration were performed 4 months on average postoperatively, and the mean follow-up time was 22 months. RESULTS: Two implants from 1 case were lost at 3 weeks after immediate implant and immediate restoration. The rest cases achieved good clinical results. Accumulative 4-year survival rate was 94.6%. CONCLUSIONS: The result of immediate implant and immediate restoration is predictable if the cases are properly selected.