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1.
Acta Crystallogr A Found Adv ; 77(Pt 6): 611-636, 2021 Nov 01.
Article in English | MEDLINE | ID: mdl-34726636

ABSTRACT

Data reduction and correction steps and processed data reproducibility in the emerging single-crystal total-scattering-based technique of three-dimensional differential atomic pair distribution function (3D-ΔPDF) analysis are explored. All steps from sample measurement to data processing are outlined using a crystal of CuIr2S4 as an example, studied in a setup equipped with a high-energy X-ray beam and a flat-panel area detector. Computational overhead as pertains to data sampling and the associated data-processing steps is also discussed. Various aspects of the final 3D-ΔPDF reproducibility are explicitly tested by varying the data-processing order and included steps, and by carrying out a crystal-to-crystal data comparison. Situations in which the 3D-ΔPDF is robust are identified, and caution against a few particular cases which can lead to inconsistent 3D-ΔPDFs is noted. Although not all the approaches applied herein will be valid across all systems, and a more in-depth analysis of some of the effects of the data-processing steps may still needed, the methods collected herein represent the start of a more systematic discussion about data processing and corrections in this field.

3.
J Rehabil Med ; 40(5): 381-6, 2008 May.
Article in English | MEDLINE | ID: mdl-18461264

ABSTRACT

OBJECTIVE: The aim of this study was to compare muscle activation patterns and patellofemoral joint morphologies between patients with knee osteoarthritis with and without patellar malalignment. SUBJECTS: The subjects were divided into 3 groups. Group A comprised 11 patients with symptomatic knee osteoarthritis without patellar malalignment. Group B comprised 14 patients with symptomatic knee osteoarthritis with patellar malalignment. Group C comprised 10 age-matched subjects with non-knee osteoarthritis as controls. METHODS: Isokinetic dynamometry with surface electromyography was used to measure maximal muscle activity in terms of vastus medialis oblique/vastus lateralis ratios. Merchant's view was taken to analyse the bony anatomy of the patellofemoral joint. Recordings were made at angular velocities of 80, 120 and 240 masculine/sec. RESULTS: The electromyographic ratios of group B were lower than groups A and C for all testing velocities (p<0.05). Group B also had larger sulcus angles, lateral patellar tilt and displacement. The electromyographic ratios correlated negatively with sulcus angles. CONCLUSION: Subjects with knee osteoarthritis with patellar malalignment exhibited an imbalance in quadriceps contraction, as confirmed by altered vastus medialis oblique/vastus lateralis ratios associated with larger sulcus angles of the patellofemoral joints. The sulcus angle may be an important contributing factor in causing abnormal patellar tracking in knee osteoarthritis.


Subject(s)
Bone Malalignment/physiopathology , Muscle, Skeletal/physiopathology , Osteoarthritis, Knee/physiopathology , Patella/physiopathology , Adult , Aged , Bone Malalignment/complications , Bone Malalignment/diagnostic imaging , Electromyography , Female , Humans , Male , Middle Aged , Muscle Contraction/physiology , Osteoarthritis, Knee/complications , Osteoarthritis, Knee/diagnostic imaging , Quadriceps Muscle/physiopathology , Radiography , Torque
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