ABSTRACT
The effect of experimental metabolic acidosis and its correction for nitrogen and energy metabolism was studied in new-born calves. It was discovered that a change in the acid-base balance towards acidosis causes a sharp increase in "ammoniogenesis", urea formation and inhibition of the tricarboxylic acid cycle, which is also observed in calves suffering from dyspepsia with symptoms of acute diarrhea. Alongside with the use of therapeutic measures for treating dyspepsia of new-born calves, it is necessary to control the acid-base balance of blood in the calves and in case of revealing the acidosis state to use means of its correction.
Subject(s)
Acidosis/metabolism , Citric Acid Cycle , Nitrogen/metabolism , Acid-Base Equilibrium , Acidosis/blood , Acidosis/drug therapy , Animals , Animals, Newborn/metabolism , Bicarbonates/pharmacology , Cattle , Sodium/pharmacology , Sodium BicarbonateABSTRACT
It has been studied how MP-15 and MP-7 preparations fed on to lactating cows affect the indices of acid-base equilibrium of their blood, nitrogen metabolism, milk yield and milk quality. It is shown that feeding on MP-15 and MP-7 preparations to cows of test groups has no negative effect on the acid-base equilibrium indices, decreases the ammonia concentration by 38.5 and 54.9%, respectively, increases the glutamine content in blood by 23.5 and 29.4%, respectively, does not affect the pyruvate, glutamate, oxaloacetate concentration and alanine-transaminase activity, increases the average daily milk yields by 2.1 and 2.3 l, respectively, and does not deteriorate the composition and physicochemical indices of milk quality.
Subject(s)
Animal Feed , Cattle/metabolism , Minerals/pharmacology , Nitrogen/metabolism , Quaternary Ammonium Compounds/pharmacology , Acid-Base Equilibrium/drug effects , Amino Acids/blood , Animals , Female , Milk/metabolismABSTRACT
Activation possibilities of redox and biosynthetic processes are studied for lactic cows with their ration supplemented by mineral-ammonium preparation MII-15. In the blood of cows from the experimental group the amount of a number of glycolysis, biocarboxylic cycle, ammonium nitrogen exchange products as well as activity of overamination enzymes vary as compared to control, which testifies to the stimulation of redox processes and protein exchange in tissues. Application of the MII-15 preparation is accompanied by an increase in the lactic productivity of cows by 8-10% on the average.