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Emerg Infect Dis ; 21(10): 1794-9, 2015 Oct.
Article in English | MEDLINE | ID: mdl-26402378

ABSTRACT

An Ehrlichia muris-like (EML) pathogen was detected among 4 patients in Minnesota and Wisconsin during 2009. We characterized additional cases clinically and epidemiologically. During 2004-2013, blood samples from 75,077 patients from all 50 United States were tested by PCR from the groEL gene for Ehrlichia spp. and Anaplasma phagocytophilum. During 2007-2013, samples from 69 (0.1%) patients were positive for the EML pathogen; patients were from 5 states: Indiana (1), Michigan (1), Minnesota (33), North Dakota (3), and Wisconsin (31). Most (64%) patients were male; median age was 63 (range 15-94) years; and all 69 patients reported likely tick exposure in Minnesota or Wisconsin. Fever, malaise, thrombocytopenia, and lymphopenia were the most common symptoms. Sixteen (23%) patients were hospitalized (median 4 days); all recovered, and 96% received doxycycline. Infection with the EML pathogen should be considered for persons reporting tick exposure in Minnesota or Wisconsin.


Subject(s)
Anaplasma phagocytophilum/pathogenicity , Anaplasmataceae/pathogenicity , Serologic Tests/methods , Ticks/parasitology , Zoonoses/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Anaplasma phagocytophilum/genetics , Anaplasmataceae/genetics , Animals , Female , Humans , Male , Middle Aged , Minnesota/epidemiology , Wisconsin/epidemiology , Zoonoses/transmission , Zoonoses/virology
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