ABSTRACT
INTRODUCTION: The fungal genus Colletotrichum is an uncommon cause of human infections. It has been implicated in cutaneous phaeohyphomycosis, artritis and keratitis secondary to traumatic implantation. CASE PRESENTATION: We report two cases of keratitis due Colletotrichum truncatum in middle-aged, immunocompetent persons without history of trauma. The aetiological agents were identified based on DNA sequencing. Azoles and echinocandins showed high minimal inhibitory concentrations while amphotericin B was ≤ 0.25 mg l-1. Both patients failed topical antifungal treatment and needed penetrating keratoplasty with a favourable outcome. CONCLUSION: C. truncatum caused keratomycosis which did not respond to topical antifungal agents. To the best of our knowledge these are the first reported cases of keratitis due to this fungus in Cuba and Latin-America and highlights the expanding spectrum of fungal agents causing eye infections.
ABSTRACT
Se evaluaron 6.520 pacientes con síntomas atribuíbles a toxoplasmosis por la presencia de anticuerpos IgG anti- Toxoplasma gondii mediante la técnica de inmunofluorescencia indirecta. El 51,27 por ciento de los evaluados resultaron positivos. El 60,85 por ciento de los pacientes con trastornos oculares son seropositivos a IgG anti- T. gondii; seguidos del 56,25 y 48,10 por ciento para aquellos con trastornos generales y gineco-obstétricos. Los síntomas o manifestaciones que evidenciaron mayor porcentaje de positividad fueron: astenia, coriorretinitis, trastornos menstruales, cefaleas y uveítis