[Endocarditis due to Candida albicans with peripheral arterial embolism and a cerebral mycotic aneurysm in an IV drug addict]. / Endocarditis por Candida albicans con embolismo arterial periférico y aneurisma micótico cerebral en adicto a drogas por vía parenteral.

Endocarditis due to Candida albicans (EC) is a rare cause of endocarditis in IV drug addicts (IVDA). Its diagnostic is usually difficult and high peripheral embolization is characteristic, and could affect big vessels. The case of a female patients (IVDA) 21 years old is discussed, who showed bilateral iliofemoral embolism and cerebral hemorrhage due to mycotic aneurysm breakage in a EC. These two complications appeared during an EC episode are exceptional. We insist in the importance of the echographic images in the suspicion diagnosis of EC.

[Severe leukopenia and thrombocytopenia and transient acquired hypogammaglobulinemia in a patient with infectious mononucleosis]. / Leucopenia y trombocitopenia intensas e hipogammaglobulinemia adquirida transitoria en un paciente con mononucleosis infecciosa.

A 30-year-old male with infectious mononucleosis by the Epstein-Barr virus who presented severe neutropenia and thrombocytopenia and type IgG acquired transitory hypogammaglobulinemia as complications during the acute period of the disease is presented. Although the etiopathogenesis of these phenomena is usually associated with an autoimmune basis, the antiplatelet and antileukocyte antibodies were negative. A bibliographic revision of the hematologic alterations of this disease was carried out and it was observed that the combination of the complications described has not been previously referred, thus, the present case may be the first observation with these characteristics.

[Cerebral toxoplasmosis in a patients with the acquired immunodeficiency syndrome. Discussion of the criteria of computerized axial tomography]. / Toxoplasmosis cerebral en un paciente con síndrome de inmunodeficiencia adquirida. Discusión de los criterios de la tomografía axial computadorizada.

Computed tomography (CT) is a sensitive noninvasive study used for the diagnosis of cerebral lesions in patients with AIDS. Toxoplasmosis is, by far, the most common opportunistic central nervous system disease (CNS) in this population; accordingly, most groups start empirical antitoxoplasma therapy if the radiological features of the lesion suggest the diagnosis. It is common, however, when CT images do not suggest toxoplasmosis, not to start empirical therapy until the investigation of the lesion with other studies has not been completed. We report a case of cerebral toxoplasmosis in a patient with AIDS which, in our opinion, illustrates that empirical antitoxoplasma therapy should be started in all CNS lesions in patients with HIV infection while etiological investigation is undertaken, independently from the appearance of the lesion in the CT.