ABSTRACT
No disponible
Subject(s)
Humans , Tobacco Use Disorder/prevention & control , Legislation as Topic , Tobacco Use Disorder/legislation & jurisprudence , National Health StrategiesABSTRACT
Lymphoepithelioma-like carcinoma of the lung is a rare tumor that is considered a subtype of undifferentiated large cell carcinoma with abundant invasion by lymphocytes. Although initially described as a tumor occurring in the nasopharynx, this type of carcinoma has since been seen in many other organs. We report the case of a 59-year-old male smoker diagnosed with lymphoepithelioma-like carcinoma.
Subject(s)
Carcinoma, Large Cell/diagnosis , Lung Neoplasms/diagnosis , Humans , Male , Middle AgedABSTRACT
No disponible
Subject(s)
Humans , Hypokalemia , Alkalosis , Hypercapnia , Respiration, Artificial , Respiration, ArtificialABSTRACT
OBJECTIVE: During physical exertion, the ventilatory response of patients with severe chronic obstructive pulmonary disease (COPD) is more rapid and shallow than that of healthy subjects. There is evidence that exercise training can alter breathing pattern in COPD patients. The purpose of the present study was to observe the effects of physical training on patients with severe COPD and to determine whether or not any possible changes were maintained over time. MATERIAL AND METHODS: Patients with severe COPD without bronchial reversibility were enrolled in a randomized controlled trial of a peripheral muscle training program carried out in a hospital setting. All enrolled patients were clinically stable, without exacerbation, and were randomly assigned to a training program of high (group A) or low (group B) intensity. RESULTS: Thirty-five men with severe COPD in stable condition (mean [SD] forced expiratory volume in 1 second at 41%[7%]) were enrolled in the study. The mean age was 64(5) years. Group A underwent training at 70(22) W and group B at 35(10) W, such that the estimated total work was 8050(2882) kJ in group A and 4044(1205) kJ in group B. Breathing pattern changes were detected in exercise tests only for group A patients, but the changes were not maintained 12 months after the end of the program. CONCLUSIONS: Intense training produces changes in the breathing pattern of patients with severe COPD. The changes are not specific to the task performed, not dependent on lactate production, and not maintained over the long term.
Subject(s)
Breathing Exercises , Exercise Therapy/methods , Pulmonary Disease, Chronic Obstructive/rehabilitation , Respiratory Muscles/physiopathology , Aged , Humans , Male , Middle Aged , Physical Education and Training , Physical Endurance , Pulmonary Disease, Chronic Obstructive/physiopathology , Respiration , Respiratory Function Tests , Treatment OutcomeABSTRACT
OBJETIVO: Durante el esfuerzo físico la respuesta ventilatoria de los enfermos con enfermedad pulmonar obstructiva crónica (EPOC) grave es más rápida y superficial que la de los sujetos sanos, y existen indicios de que el entrenamiento físico podría cambiar el patrón ventilatorio de estos pacientes. El propósito del presente estudio fue comprobar los efectos que el entrenamiento físico de los pacientes con EPOC grave tiene sobre el patrón ventilatorio, así como determinar o no el mantenimiento de los posibles cambios producidos en el tiempo. MATERIAL Y MÉTODO: Se realizó un estudio aleatorio y controlado con pacientes con EPOC grave sin reversibilidad bronquial. En estos pacientes se efectuó una intervención mediante entrenamiento físico. Los pacientes fueron remitidos al hospital para entrenamiento muscular periférico, todos ellos en situación clínica estable, sin exacerbación, y fueron asignados a dos programas diferentes de entrenamiento físico. RESULTADOS: Se estudiaron 35 pacientes varones con EPOC grave, estables (volumen espiratorio forzado en el primer segundo del 41 ñ 7 por ciento), con una edad media de 64 ñ 5 años, divididos en dos grupos con diferente potencia media estimada de entrenamiento (grupo A: 70 ñ 22 W; grupo B: 35 ñ 10 W) y trabajo total desarrollado (grupo A: 8.050 ñ 2.882 kJ; grupo B: 4.044 ñ 1.205 kJ). Sólo se objetivaron cambios en el patrón ventilatorio durante el ejercicio realizado durante la prueba de esfuerzo en el grupo A, que no se mantuvieron a los 12 meses de finalizado el programa. CONCLUSIONES: El entrenamiento intenso produce cambios en el patrón ventilatorio de los pacientes con EPOC grave que son inespecíficos de la tarea e independientes de la producción de lactato, y que no se mantienen a largo plazo (AU)
