1.
J Am Acad Dermatol
; 43(5 Pt 1): 881-2, 2000 Nov.
Article
in English
| MEDLINE
| ID: mdl-11050603
2.
South Med J
; 93(7): 650-5, 2000 Jul.
Article
in English
| MEDLINE
| ID: mdl-10923948
ABSTRACT
BACKGROUND: The prevalence of nonmelanoma skin cancer in the United States is alarming. It can be most appropriately treated if the earliest manifestation of cutaneous squamous cell carcinoma is recognized. METHODS: Clinical, histologic, and molecular biology, considerations were reviewed to determine whether actinic keratosis is the earliest clinical manifestation of cutaneous squamous cell carcinoma. RESULTS: The clinical, histologic, and molecular parameters of actinic keratosis are those of squamous cell carcinoma. CONCLUSION: Actinic keratosis does not transform, convert, or progress into cutaneous squamous cell carcinoma but is the earliest clinically recognizable manifestation of this malignancy.
Subject(s)
Carcinoma, Squamous Cell/pathology , Keratosis/pathology , Skin Neoplasms/pathology , Carcinoma, Squamous Cell/genetics , Cell Transformation, Neoplastic/pathology , Epidermis/pathology , Humans , Keratinocytes/pathology , Keratosis/genetics , Molecular Biology , Neoplasm Invasiveness , Precancerous Conditions/pathology , Prevalence , Skin Neoplasms/genetics , Terminology as Topic
3.
J Cutan Med Surg
; 4(1): 12-3, 2000 Jan.
Article
in English
| MEDLINE
| ID: mdl-10744449