ABSTRACT
Diffuse bilateral uveal melanocytic proliferation is a rare paraneoplastic ophthalmologic syndrome. The increase in life expectancy in oncology partly explains the gradual increase in its incidence. In almost half of the cases, the syndrome manifests itself before the diagnosis of primary neoplasia. It should be suspected in cases of bilateral uveal pigmented lesions that do not meet the clinical criteria for other known eye pathologies. Legal blindness occurs for the majority of patients during the first year after the initial clinical presentation. Death, due to the severity of the underlying pathology, occurs statistically within three years. Here we display the case of such a diffuse bilateral uveal melanocytic proliferation in a patient with relapsed colonic adenocarcinoma, initially treated for age-related macular degeneration.
La prolifération mélanocytique uvéale bilatérale diffuse est un syndrome paranéoplasique ophtalmologique rare. L'augmentation de l'espérance de vie en oncologie explique, en partie, la majoration progressive de son incidence. Dans près de la moitié des cas, le syndrome se manifeste antérieurement au diagnostic de la néoplasie primaire. Il doit être suspecté en cas de lésions pigmentées uvéales bilatérales ne répondant pas aux critères cliniques d'autres pathologies oculaires connues. La cécité légale s'établit chez la majorité des patients durant la première année suivant la présentation clinique initiale. Un décès, dû à la sévérité de la pathologie sous-jacente, survient presque toujours dans les trois ans. Nous rapportons ici le cas d'une telle prolifération mélanocytique uvéale bilatérale diffuse, chez une patiente atteinte d'un adénocarcinome colique en rechute, traitée initialement pour une dégénérescence maculaire liée à l'âge.
Subject(s)
Adenocarcinoma , Paraneoplastic Syndromes , Uveal Diseases , Cell Proliferation , Humans , MelanocytesABSTRACT
We present the case of a patient who had a decrease of the visual acuity associated with headaches, diagnosed as vogt-koyanagi-harada syndrome. This is a rare multisystemic pathology that affects organs with high concentration of melanocytes. This syndrome needs to be identified on time as corticotherapy has to be administrated urgently. This paper also summarizes the literature on this disease.
Nous présentons le cas d'une patiente souffrant d'une baisse d'acuité visuelle associée à des céphalées. L'investigation a permis de mettre en évidence un syndrome de vogt-koyanagi-harada. Il s'agit d'une pathologie multi-systémique rare, affectant les organes présentant une haute concentration de mélanocytes. Il est important d'en poser rapidement le diagnostic pour administrer une corticothérapie. L'étude de ce cas est complétée par une revue de la littérature sur le sujet.
Subject(s)
Uveomeningoencephalitic Syndrome/diagnosis , Eye/diagnostic imaging , Female , Headache/etiology , Humans , Leukocytosis/etiology , Visual Acuity , Young AdultABSTRACT
OMC seems to be more frequently associated with combined surgery: cataract and ERM extraction than with a two steps surgery.
Subject(s)
Cataract Extraction/methods , Epiretinal Membrane/surgery , Ophthalmologic Surgical Procedures/methods , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , ReoperationABSTRACT
Among photosensitive patients, the use of colored filters sometimes leads to a clear improvement of comfort. After a general review of theory, we start on the way we take care of these patients and the way filters are fitted and made. We only present here a preliminary work. A subsequent study or accurate informations of colored filters will be published later. The aim is to set up a methodic procedure in order to find the best selection of the recommended spectral curve and the best way to follow the progress of the patient as regards the wearing and the effect of the filter. An overview of our cases is presented.
Subject(s)
Filtration/instrumentation , Photosensitivity Disorders/therapy , Color , Humans , Pilot ProjectsABSTRACT
The treatment of the central retinal vein occlusion (CRVO) is a debated question. Isovolaemic haemodilution known for its beneficial effects on the tissue microcirculation has shown encouraging results. A first study on 14 patients seems to indicate beneficial effects of isovolaemic haemodilution versus spontaneous evolution.
