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Schweiz Med Wochenschr ; 106(13): 438-43, 1976 Mar 27.
Article in German | MEDLINE | ID: mdl-817393

ABSTRACT

The clinical course and biopsy and autopsy findings in a patient with asymmetrical polyneuropathy in Waldenström's disease are reported. Under steroid therapy the patient developed mild diabetes mellitus. In the light of the course of the disease, a causal relationship between the hematologic disease and the peripheral neuropathy is assumed. Although a peripheral nerve could not be examined on autopsy, strong lymphocytic infiltration in the autonomic nerves seems to point to a similar pathogenetic mechanism in the development of polyneuropathy. The other possible causal factors are discussed with reference to the small number of reports in the literature.


Subject(s)
Neurologic Manifestations , Waldenstrom Macroglobulinemia/complications , Autonomic Nervous System/pathology , Humans , Hypesthesia/etiology , Immunoglobulin M , Lymphocytes , Male , Melphalan/therapeutic use , Middle Aged , Myocardium/cytology , Paralysis/etiology , Pulmonary Edema/etiology , Waldenstrom Macroglobulinemia/drug therapy
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