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7.
Z Gesamte Hyg ; 36(3): 130-1, 1990 Mar.
Article in German | MEDLINE | ID: mdl-2186576

ABSTRACT

The "Haber's Constant", the product of concentration (in ppm) and time (in minutes) to cause death, was mainly used in connection with the development of chemical warfare agents during World War I. But up to now the Haber's Constant is important to compare toxic gases tested on many different species of animals in research and development as well as in hygiene practice. The very first experiments in this field were done long before Haber's work in 1900 by Ernest Warren (London).


Subject(s)
Toxicology/history , Gas Poisoning/history , History, 20th Century , Humans
17.
Arch Geschwulstforsch ; 46(6): 437-42, 1976.
Article in German | MEDLINE | ID: mdl-999453

ABSTRACT

Wistar rats evolved many malignant tumors of different localisation. The tumors grew in the time of 8-14 months after oral application of asbestos filters which contained 53% Chrysotile asbestos. The number of tumors was statistically significant different not only in comparison to a control group which got talc only, but also to an untreated control group. The localisation of the tumors varied and so conclusions about organ specifity can not be drawn, when asbestos is applicated orally.


Subject(s)
Asbestos/adverse effects , Carcinogens , Neoplasms, Experimental/chemically induced , Administration, Oral , Animals , Asbestos/administration & dosage , Cricetinae , Female , Filtration , Male , Rats , Time Factors
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