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1.
Cancer Radiother ; 14(1): 65-8, 2010 Jan.
Article in French | MEDLINE | ID: mdl-19695929

ABSTRACT

PURPOSE: Evaluation of the results of perioperative interstitial brachytherapy with low dose-rate (LDR) Ir-192 in the treatment of keloid scars. PATIENTS AND METHODS: We performed a retrospective analysis of 73 histologically confirmed keloids (from 58 patients) resistant to medicosurgical treated by surgical excision plus early perioperative brachytherapy. All lesions were initially symptomatic. Local control was evaluated by clinical evaluation. Functional and cosmetic results were assessed in terms of patient responses to a self-administered questionnaire. RESULTS: Median age was 28 years (range 13-71 years). Scars were located as follows: 37% on the face, 32% on the trunk or abdomen, 16% on the neck, and 15% on the arms or legs. The mean delay before loading was four hours (range, 1-6h). The median dose was 20Gy (range, 15-40Gy). Sixty-four scars (from 53 patients) were evaluated. Local control was 86% (follow-up, 44.5 months; range, 14-150 months). All relapses occurred early - within 2 years posttreatment. At 20 months, survival without recurrence was significantly lower when treated lengths were more than 6cm long. The rate was 100% for treated scars below 4.5cm in length, 95% (95% CI: 55-96) for those 4.5-6cm long, and 75% (95% CI: 56-88) beyond 6cm (p=0.038). Of the 35 scars (28 patients) whose results were reassessed, six remained symptomatic and the esthetic results were considered to be good in 51% (18/35) and average in 37% (13/35) (median follow-up, 70 months; range, 16-181 months). CONCLUSION: Early perioperative LDR brachytherapy delivering 20Gy at 5mm reduced the rate of recurrent keloids resistant to other treatments and gave good functional results.


Subject(s)
Brachytherapy/methods , Keloid/radiotherapy , Perioperative Care , Adolescent , Adult , Aged , Esthetics , Female , Humans , Keloid/surgery , Male , Middle Aged , Radiotherapy Dosage , Retrospective Studies , Secondary Prevention , Young Adult
2.
Ann Chir Plast Esthet ; 42(1): 70-4, 1997 Feb.
Article in French | MEDLINE | ID: mdl-9768139

ABSTRACT

With a case of thoraco-lumbar defect, the authors discuss about different procedures to cover it. In this place, the better procedure is certainly the latissimus dorsi flap, in all combinations. The indication for omentoplasty at this spinal site should not be performed by first intention but by exclusion of other procedures, as in the case considered by the authors. It was a 37-year-old man, paraplegic from the age of 16, with a deep chronic spinal wound, secondary to sepsis of a posterior segmental fixations. A staphylococcus aureus infection which developed as a surgical complication was initially treated with antibiotics and surgical cleaning procedures without removing instrumentation. However, the infection remained active and the material was finally removed. Spinal immobilisation was strengthened by external fixation. The area was cleared of all suspect material, including bone graft, leaving a wide back-wound open to the spine. Spontaneous healing was first attempted, but the size and the chronicity of the wound led us to use pedicled greater omentum to close the defect. The omentum was pedicled on the right gastroepiploic vessels and transferred to the back wound through the posterior abdominal wall muscles, next to the right kidney. This procedure allows rapid healing. In association with suitable antibiotics, it has prevented any recurrent infection after 18 months of follow-up. It was no feasible to cover the wound with a latissimus dorsi flap, considering the importance of this muscle in the movements of a paraplegic and considering the initial impossibility of removing the external fixation.


Subject(s)
Lumbar Vertebrae/surgery , Omentum/transplantation , Surgical Flaps , Thoracoplasty/adverse effects , Adult , Chronic Disease , Humans , Lumbar Vertebrae/abnormalities , Male , Postoperative Complications/microbiology , Sepsis/microbiology , Staphylococcal Infections/microbiology , Thorax/abnormalities , Wound Healing
3.
Ann Chir Plast Esthet ; 41(6): 660-5, 1996 Dec.
Article in French | MEDLINE | ID: mdl-9768175

ABSTRACT

Based on a case of recurrence of a dermatofibrosarcoma protuberans of the abdominal wall, the authors discuss the need for initial wide resection of this type of skin tumour and the possibilities of repair of extensive full thickness defects of the abdominal wall by means of a latissimus dorsi myocutaneous free flap.


Subject(s)
Abdominal Muscles/surgery , Dermatofibrosarcoma/surgery , Muscle, Skeletal/transplantation , Neoplasms, Connective Tissue/surgery , Surgical Flaps , Abdominal Muscles/diagnostic imaging , Dermatofibrosarcoma/diagnostic imaging , Female , Humans , Middle Aged , Neoplasm Recurrence, Local , Neoplasms, Connective Tissue/diagnostic imaging , Tomography, X-Ray Computed
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