Recent HIV infection and associated factors among newly diagnosed HIV cases in the Southwest Ethiopia Regional State: HIV case-based surveillance analysis (2019-2022).

BACKGROUND: Globally, there were an estimated 39 million people living with HIV with 1.3 million new HIV infections by the end of 2023. The Sub-Saharan Africa accounted 51% of new HIV infections. HIV case-based Surveillance collects data on newly diagnosed HIV cases, recent HIV infections, and other sentinel events, aiding evidence-based decision making. There is limited evidence on these in Ethiopia. The objective of this study is to determine the incidence proportion of recent infections and associated factors among newly diagnosed HIV cases and their distribution by person, place, and time in the Southwest Ethiopia Regional State. METHODS: A retrospective analysis was conducted on HIV case-based surveillance dataset (July 2019 to June 2022) from the Southwest Ethiopia Regional State. Recent HIV infection is an infection that acquired within the last 12 months as diagnosed by Asante recency test kits. Data were analyzed using SPSS version 26. ArcGIS version 10.8 was used for mapping recent infections. Logistic regression was employed to identify factors associated with recent infections. In multivariable logistic regression analysis, variables with p-value < 0.05 and an adjusted odds ratio with 95% confidence interval were considered to declare significant association. RESULTS: A total of 1,167 newly diagnosed HIV cases (eligible cases) were identified. Among these, 786 (67.3%) recency tests were performed. The mean age of individuals with recent infection was 28.4 years. The proportion of recent infection is 89 (11.3%, 95% CI: 11.2, 11.5%). The highest proportion of recent infection is reported from the West Omo zone (42.9%), whereas 13.2% in Bench Sheko zone. Recent infection is significantly associated with age 15-24 years [AOR = 7.14, 95%CI: 2.89,17.57], age 25-34 years [AOR = 5.34, 95%CI: 2.20,12.94], females [AOR = 2.03, 95%CI: 1.26,3.25], and contact history with the index case [AOR = 0.48, 95%CI: 0.28, 0.83]. The incidence of recent infection increased from 86 (in 2019/20) to 132 (in 2022) recent infections per 1,000 newly diagnosed cases. CONCLUSIONS: Recent HIV infection is a public health concern in the Southwest Ethiopia Regional State with an increasing incidence. Targeted prevention efforts are necessary, especially for females and younger people.

Assessment of COVID-19 prevention practice and associated factors in Jimma town, Ethiopia: A mixed study.

Background: COVID-19 has affected the mental and physical wellbeing, social structure, countries' economy as well as individuals and community resilience, trust, and inequalities among societies. However, now almost all of the activities have been returned to the pre-corona era, despite the emergence of new strains and the spread of the disease. Hence, this study was conducted to assess COVID-19 prevention practice and the associated factors. Materials and methods: A community-based cross-sectional study triangulated with the qualitative findings was conducted in Jimma town, Oromia, Ethiopia. A total of 422 sample households were involved in the quantitative study. The quantitative data were collected using a structured questionnaire and 12 key informants were also interviewed for the qualitative part. The quantitative data were processed and entered into the Epi Data version 4.6 (software) and analyzed using SPSS 26.0. Similarly, the qualitative data were analyzed using ATLASti.7.1.04 software package. Descriptive statistics and binary logistics regression (p < 0.25) were conducted to identify the candidate variable for multivariable logistics regression analysis (p < 0.05) and a 95% confidence interval was used to establish the level of significance of the variables with the practice. Results: Interviews were conducted with a total of 422 participants, yielding a response rate of 100%. Good preventive practices were found to be adopted by 13.3% of the respondents. People aged ≥ 50 years, [AOR = 2.85, 95%, CI = 1.246-0.53] who recovered from COVID-19, [AOR = 2.41, 95%, CI = 1.184-0.92], had chronic diseases [AOR = 3.70, 95%, CI = 1.887-0.25], and living with COVID-19 high risk [AOR = 2.96, 95%, CI = 1.475-0.991 were independently associated with good preventive practices. Conclusion: In this study, it was understood that there were poor COVID-19 preventive practices among the study participants. There was a disparity in adherence to the preventive practices in relation to (i.e., 50 and above years) the experience of contracting COVID-19 and people aged above 65 years old living with the high-risk group. In addition, the community had different misconceptions or risk perceptions related to COVID-19 infection and preventive practices. This highlights the need to design health education programs and implement risk and/or social and behavior change communication interventions to change perceptions or misconceptions of people or community members to bring about the desired behavioral change and prevent the spread of COVID-19.