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Clostridium difficile strains from community-associated infections.

Limbago, Brandi M; Long, Cherie M; Thompson, Angela D; Killgore, George E; Hannett, George E; Havill, Nancy L; Mickelson, Stephanie; Lathrop, Sarah; Jones, Timothy F; Park, Mahin M; Harriman, Kathleen H; Gould, L Hannah; McDonald, L Clifford; Angulo, Frederick J.

J Clin Microbiol ; 47(9): 3004-7, 2009 Sep.

Article in English | MEDLINE | ID: mdl-19571021

ABSTRACT

Clostridium difficile isolates from presumed community-associated infections (n = 92) were characterized by toxinotyping, pulsed-field gel electrophoresis, tcdC and cdtB PCR, and antimicrobial susceptibility. Nine toxinotypes (TOX) and 31 PFGE patterns were identified. TOX 0 (48, 52%), TOX III (18, 20%), and TOX V (9, 10%) were the most common; three isolates were nontoxigenic.

Subject(s)

Clostridioides difficile/classification , Clostridioides difficile/isolation & purification , Community-Acquired Infections/microbiology , Enterocolitis, Pseudomembranous/microbiology , ADP Ribose Transferases/genetics , Bacterial Proteins/genetics , Bacterial Toxins/analysis , Bacterial Typing Techniques , Cluster Analysis , DNA Fingerprinting , Electrophoresis, Gel, Pulsed-Field , Genotype , Humans , Microbial Sensitivity Tests , Molecular Epidemiology , Polymerase Chain Reaction/methods , Repressor Proteins/genetics

ABSTRACT

Subject(s)

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