ABSTRACT
Objectives: To describe the frequency of brain tissue donation for research purposes by families of individuals that committed suicide. Methods: All requests for brain tissue donation to a brain biorepository made to the families of individuals aged 18-60 years who had committed suicide between March 2014 and February 2016 were included. Cases presenting with brain damage due to acute trauma were excluded. Results: Fifty-six cases of suicide were reported. Of these, 24 fulfilled the exclusion criteria, and 11 others were excluded because no next of kin was found to provide informed consent. Of the 21 remaining cases, brain tissue donation was authorized in nine (tissue fragments in seven and the entire organ in two). Conclusions: Donation of brain tissue from suicide cases for research purposes is feasible. The acceptance rate of 42.8% in our sample is in accordance with international data on such donations, and similar to rates reported for neurodegenerative diseases.
Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Young Adult , Suicide/statistics & numerical data , Tissue Donors/statistics & numerical data , Brain/anatomy & histology , Biomedical Research/statistics & numerical data , Autopsy/statistics & numerical data , Tissue Banks/statistics & numerical data , Brazil , Neurodegenerative Diseases/pathology , Informed Consent/statistics & numerical dataABSTRACT
OBJECTIVES:: To describe the frequency of brain tissue donation for research purposes by families of individuals that committed suicide. METHODS:: All requests for brain tissue donation to a brain biorepository made to the families of individuals aged 18-60 years who had committed suicide between March 2014 and February 2016 were included. Cases presenting with brain damage due to acute trauma were excluded. RESULTS:: Fifty-six cases of suicide were reported. Of these, 24 fulfilled the exclusion criteria, and 11 others were excluded because no next of kin was found to provide informed consent. Of the 21 remaining cases, brain tissue donation was authorized in nine (tissue fragments in seven and the entire organ in two). CONCLUSIONS:: Donation of brain tissue from suicide cases for research purposes is feasible. The acceptance rate of 42.8% in our sample is in accordance with international data on such donations, and similar to rates reported for neurodegenerative diseases.
Subject(s)
Biomedical Research/statistics & numerical data , Brain , Suicide/statistics & numerical data , Tissue Donors/statistics & numerical data , Adolescent , Adult , Autopsy/statistics & numerical data , Brain/anatomy & histology , Brazil , Female , Humans , Informed Consent/statistics & numerical data , Male , Middle Aged , Neurodegenerative Diseases/pathology , Tissue Banks/statistics & numerical data , Young AdultABSTRACT
OBJECTIVE: The aim of this study was to verify the clinical applicability of the Nursing Outcomes Classification (NOC) to the evaluation of cancer patients with a nursing diagnosis of acute or chronic pain in a palliative care unit. METHOD: A prospective longitudinal study performed on a sample of 13 adult cancer patients in a palliative care unit. Patients were followed for at least 4 days. Data were collected with an instrument containing eight nursing outcomes and nineteen NOC indicators. Statistical analysis was performed using generalized estimating equation models. RESULTS: The following outcome and indicator scores changed significantly over the course of the study: reported pain and length of pain episodes in the pain level outcome; social relationships in the personal well-being outcome; respirator rate in the vital signs outcome; and describes causal factors in the pain control outcome. CONCLUSION: The NOC outcomes and indicators included in this study were able to successfully evaluate the clinical evolution of cancer patients in palliative care. These scores proved to be applicable for use in palliative nursing care.
