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1.
J Am Acad Dermatol ; 35(4): 601-5, 1996 Oct.
Article in English | MEDLINE | ID: mdl-8859290

ABSTRACT

This review of epidemiologic, clinical, and psychosocial/psychobehavioral data related to genital herpes simplex virus infection details the increasing incidence of herpes simplex virus infection in the United States and summarizes the data regarding the safety and efficacy of chronic and acute antiviral therapy with acyclovir. It additionally establishes the validity of psychosocial intervention as an adjunct to pharmacologic therapy for patients with recurrent genital herpes.


Subject(s)
Herpes Genitalis/therapy , Acyclovir/therapeutic use , Antiviral Agents/therapeutic use , Combined Modality Therapy , Herpes Genitalis/epidemiology , Herpes Genitalis/physiopathology , Herpes Genitalis/psychology , Humans , Incidence , Psychotherapy , Recurrence , United States/epidemiology
2.
J Psychosom Res ; 33(2): 161-6, 1989.
Article in English | MEDLINE | ID: mdl-2724192

ABSTRACT

Psychosocial factors (emotional distress, stress, health locus of control, and social support) and genital herpes activity (episode frequency, severity, and duration) were assessed for 46 individuals with recurrent genital herpes infections (HSV) in order to predict psychosocial status associated with herpes episodes. Multiple regression analyses revealed that stress and emotional distress accounted for 52% of HSV episode frequency variance, whereas 49% of the episode severity variance was determined by emotional distress and health locus of control. The buffering effects of time and health locus of control were functional only for herpes frequency. Linear predictive models appear to offer a better opportunity for understanding how psychosocial factors affect genital herpes outbreaks than do interactive or buffering models. Results were discussed in terms of the biopsychosocial model of health.


Subject(s)
Herpes Genitalis/psychology , Adolescent , Adult , Affective Symptoms/complications , Female , Herpes Genitalis/etiology , Humans , Internal-External Control , Male , Models, Psychological , Recurrence , Stress, Psychological/complications , Time Factors
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