ABSTRACT
The associations of parental moral disengagement, guilt, prosocial behavior, and anger, with their children's maladaptive anger was examined. 98 college undergraduate students and their parents participated. Both students and parents completed the Anger Response Inventory, the Mechanism of Moral Disengagement Scale, the Texas Social Behavior Inventory, the Fear of Punishment Scale, and the Need for Reparation Scale. A multiple regression analysis was performed to assess the students' variables which predicted maladaptive anger. Only moral disengagement was a predictor of the students' maladaptive anger. Subsequent multiple regression analyses were used to examine whether parental variables predict students' anger. Fathers' maladaptive anger, and prosocial skills were significantly related to students' maladaptive anger. Maternal variables produced an increase in the multiple R similar to the fathers', but none of the individual measures were significantly associated with the students' maladaptive anger.
Subject(s)
Anger , Cognition , Parents/psychology , Adaptation, Psychological , Adult , Female , Guilt , Humans , Male , Regression Analysis , Surveys and QuestionnairesABSTRACT
OBJECTIVE: To evaluate the immune response in Peruvian children following measles vaccination. METHODS: Fifty-five Peruvian children received Schwarz measles vaccine (about 10(3) plaque forming units) at about 9 months of age. Blood samples were taken before vaccination, then twice after vaccination: one sample at between 1 and 4 weeks after vaccination and the final sample 3 months post vaccination for evaluation of immune cell phenotype and lymphoproliferative responses to measles and non-measles antigens. Measles-specific antibodies were measured by plaque reduction neutralization. FINDINGS: The humoral response developed rapidly after vaccination; only 4 of the 55 children (7%) had plaque reduction neutralization titres <200 mlU/ml 3 months after vaccination. However, only 8 out of 35 children tested (23%) had lymphoproliferative responses to measles antigens 3-4 weeks after vaccination. Children with poor lymphoproliferative responses to measles antigens had readily detectable lymphoproliferative responses to other antigens. Flow cytometric analysis of peripheral blood mononuclear cells revealed diffuse immune system activation at the time of vaccination in most children. The capacity to mount a lymphoproliferative response to measles antigens was associated with expression of CD45RO on CD4+ T-cells. CONCLUSION: The 55 Peruvian children had excellent antibody responses after measles vaccination, but only 23% (8 out of 35) generated detectable lymphoproliferative responses to measles antigens (compared with 55-67% in children in the industrialized world). This difference may contribute to the less than uniform success of measles vaccination programmes in the developing world.