ABSTRACT
BACKGROUND: Some lesions not included in the Banff classification, such as inflammation in the scarred areas and total inflammation, have been described to have prognostic value in the evaluation of graft biopsies. Our aim was to reassess kidney graft biopsies and study the impact of histopathologic lesions, both those graded in the Banff classification and those related to inflammation, on the graft function and evolution. METHODS: We selected 20 biopsies exhibiting chronic pathology without a specific phenotype, and we reevaluated them with the use of a modified Banff score. RESULTS: We found statistically significant association between the presence of total inflammation (P = .048; P = .038), the presence of inflammation in scared area (P = .037; P = .018), and creatinine at the time of renal biopsy and 1 year after the renal biopsy, respectively. CONCLUSIONS: Our results suggest that the presence of both inflammation in the scarred areas and total inflammation are related to renal function at the time of the biopsy and to renal function 1 year after the biopsy.
Subject(s)
Kidney Transplantation , Kidney/pathology , Transplants/pathology , Biopsy , Chronic Disease , Cicatrix/pathology , Creatinine/metabolism , Female , Graft Rejection/pathology , Humans , Male , Middle Aged , Nephrectomy/methods , Nephritis/pathology , Nephritis/physiopathology , Organ Dysfunction Scores , Prognosis , Transplants/physiopathologyABSTRACT
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Subject(s)
Humans , Female , Cytomegalovirus Infections/complications , Lupus Nephritis/complications , Cytomegalovirus/pathogenicity , Colitis/microbiology , Lupus Erythematosus, Systemic/complications , Immunosuppressive Agents/therapeutic useSubject(s)
Colitis/etiology , Cytomegalovirus Infections/complications , Opportunistic Infections/complications , Antigens, Viral/analysis , Colonoscopy , Cytomegalovirus/immunology , Cytomegalovirus Infections/diagnosis , Diagnosis, Differential , Female , Humans , Immunocompromised Host , Immunosuppressive Agents/administration & dosage , Immunosuppressive Agents/adverse effects , Immunosuppressive Agents/therapeutic use , Lupus Erythematosus, Systemic/complications , Lupus Erythematosus, Systemic/drug therapy , Lupus Nephritis/complications , Lupus Nephritis/drug therapy , Methylprednisolone/administration & dosage , Methylprednisolone/adverse effects , Methylprednisolone/therapeutic use , Mycophenolic Acid/administration & dosage , Mycophenolic Acid/adverse effects , Mycophenolic Acid/analogs & derivatives , Mycophenolic Acid/therapeutic use , Nocardia Infections/complications , Opportunistic Infections/diagnosis , Pneumatosis Cystoides Intestinalis/etiology , Respiratory Tract Infections/complicationsABSTRACT
Presentation of one case of fibrous pseudotumor of epididymis in a 33 year-old patient. Final diagnosis was achieved after surgical exeresis and its pathoanatomical examination. Etiopathogeny, clinic presentation and therapeutical approach are reviewed. Considering, in general, the clinical inespecificity of intrascrotal processes, we believe it is important to know this entity in order to be in a position to address differential diagnosis with truly neoplastic processes.