Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
J Matern Fetal Neonatal Med ; 30(15): 1836-1840, 2017 Aug.
Article in English | MEDLINE | ID: mdl-27562126

ABSTRACT

OBJECTIVE: The aim of this study was to determine malondialdehyde (MDA) concentration as an oxidative stress marker and total antioxidant capacity (TAC) in pregnancy before and after perinatal event. METHODS: This study was performed on 200 healthy full-term pregnant women admitted to pregnancy resolution in Maternal-Child Hospital of Durango, Mexico. Oxidative stress and TAC were assessed through detection of lipid peroxidation by quantitation of thiobarbituric acid-reactive substances (TBARS) and TAC through ferric reducing ability of the plasma (FRAP). RESULTS: Our results showed increased levels of MDA after vaginal delivery (VD). TAC was also increased after obstetric event, but it did not differ between VD and caesarean section. CONCLUSIONS: We demonstrated that MDA concentrations are increased two hours after obstetric event, and this increase correlates with VD. The TAC was increased as a compensatory mechanism during obstetric event. Another important finding is that women receiving analgesia administration in VD, as well as dexamethasone administration in caesarean section, experienced a protector effect that decreased MDA levels.


Subject(s)
Delivery, Obstetric , Malondialdehyde/blood , Oxidative Stress/physiology , Adult , Analgesia, Obstetrical , Antioxidants/analysis , Biomarkers/blood , Cesarean Section , Dexamethasone/administration & dosage , Female , Humans , Lipid Peroxidation , Male , Mexico , Pregnancy , Pregnancy Outcome , Thiobarbituric Acid Reactive Substances/analysis , Young Adult
SELECTION OF CITATIONS
SEARCH DETAIL
...