ABSTRACT
OBJECTIVE: Premature infants, especially those born less than 1500 g, often exhibit slow overall growth after birth and lack of early nutritional support may be an important element. We tested the hypothesis that early administration of amino acids (within the first few hours of life) to infants born at less than 1500 g would be associated with fewer infants that were less than the 10th percentile at 36 weeks post-conceptual age than infants that received amino acids after the first 24 h of life. STUDY DESIGN: A prospective intervention of early amino-acid (EAA) supplementation, began before 24 h of life, in preterm infants, <1500 g, was compared to a retrospective cohort of preterm infants receiving late amino-acid (LAA) supplementation, began after 24 h of life. The primary outcome variable was the proportion of infants at less than the 10th percentile at 36 weeks post-conceptual age. RESULT: Fewer infants fell below the 10th percentile (P<0.001) in the EAA group. Furthermore, infants in the EAA groups had significantly greater weight gains than did the LAA group (P<0.003) after adjusting for gestational age and time from birth to discharge. In addition, shorter duration of parenteral nutrition was associated with EAA supplementation (P<0.001). CONCLUSION: A prospective strategy of EAA in preterm infants <1500 g was associated with an improved weight gain, suggesting that nutrition that included amino acids may be critical during the first 24 h of life.
Subject(s)
Amino Acids/administration & dosage , Infant, Low Birth Weight/growth & development , Infant, Premature/growth & development , Parenteral Nutrition/methods , Weight Gain , Drug Administration Schedule , Humans , Infant, Newborn , Intensive Care Units, Neonatal , Prospective StudiesABSTRACT
In this study, MIE values measured with two different explosion tubes, HARTMANN and MIKE 3, are compared. Generally, MIKE 3 apparatus provides MIE results, which are equal or lower to those measured with the HARTMANN apparatus; this is particularly true for the energy ranges between 1 and 10mJ and higher than 100mJ. Differences observed can modify samples classification according to their sensitivity to electrostatic ignition sources. Nevertheless, ignition of a dust cloud by an electrostatic discharge is complex, and implies a different mechanism from that occurring during MIE tests. Thus, it seems difficult to synchronise dust dispersion and spark triggering to obtain optimal concentration in the spark area. Moreover, spark characteristics such as duration or energy feeding rate of spark cannot reproduce exactly industrial-world ones. On this point, it is not possible to conclude if characteristics of MIKE 3 electric circuit, e.g., resistance and inductance, are more relevant than HARTMANN circuit ones.
Subject(s)
Equipment and Supplies , Explosions/prevention & control , Static ElectricityABSTRACT
BACKGROUND: Idiopathic capillary hyperpermeability syndrome is expressed by episodes of hypovolemic shock with normal consciousness. CASE REPORT: A 61-year-old man had a history of recurrent shock. During the shock episodes, blood pressure was non-measurable and laboratory tests showed polycythemia, low serum protein and monoclonal immunoglobulinemia. The patient also developed pneumocystosis and had an infra-His block. DISCUSSION: The final diagnosis was idiopathic capillary hyperpermeability syndrome. This rare syndrome associates recurrent shock with IgG monoclonal immunoglobulinemia and, at the time of the shock episodes, increased hematocrit with paradoxical fall in serum protein.
