1.
Toxicon
; 150: 175-179, 2018 Aug.
Article
in English
| MEDLINE
| ID: mdl-29782950
ABSTRACT
For the first time, alcohol extracts of Atelopus hoogmoedi from the Guiana Shield in Suriname and Guyana were analyzed for the presence of tetrodotoxin (TTX) and of its analogues by high resolution hydrophilic interaction liquid chromatography/mass spectrometry. One specimen from Suriname was found to contain TTX and 4-epiTTX. Using a monoclonal antibody-based immunohistochemical staining technique, TTX was localized mainly in the granular glands and epithelium of the skin, but not in internal organs except liver showing weak TTX-positive reaction. In two specimens collected in Guyana, none of the toxins were detected.
Subject(s)
Bufonidae/physiology , Tetrodotoxin/metabolism , Animal Distribution , Animals , South America
2.
Curr Biol
; 26(19): R870-R872, 2016 10 10.
Article
in English
| MEDLINE
| ID: mdl-27728785
ABSTRACT
In this Quick Guide, Lorentz et al. discuss the function of tetrodotoxin and its distribution in the animal kingdom.