1.
J Surg Res
; 88(2): 114-9, 2000 Feb.
Article
in English
| MEDLINE
| ID: mdl-10644475
ABSTRACT
This paper represents a contribution to researchers employing "in vivo" models in experimental surgery in order to obtain more reliable results in accordance with current legislation and Russel's "three R" statement: refinement, reduction, and replacement. After general consideration about the definition of pain and stress concerning laboratory animals, the authors suggest making an evaluation of the experimental protocol before approval by the local committee to allow assessment in terms of the costs/benefits of experimental research employing live animals.
Subject(s)
Animals, Laboratory/psychology , Pain/veterinary , Stress, Physiological/veterinary , Surgical Procedures, Operative/psychology , Animals , Pain/etiology , Stress, Physiological/etiology
2.
Ann Ist Super Sanita
; 20(4): 271-4, 1984.
Article
in Italian
| MEDLINE
| ID: mdl-6546274