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Nanomedicine (Lond) ; 19(2): 163-179, 2024 01.
Article in English | MEDLINE | ID: mdl-38284393

ABSTRACT

Background & aims: Inflammatory bowel disease (IBD) is a condition characterized by chronic inflammation of the gastrointestinal tract, manifesting as either Crohn's disease (CrD) or ulcerative colitis (UC). Current treatment options for CrD and UC primarily focus on symptom management. In recent years, advancements in nanotechnology have increased the clinical applicability of nanoparticles (NPs) in treating IBD. This review explores the current research on NP-mediated drug-delivery systems for IBD treatment and assesses its advantages and limitations. Results: The authors examine diverse nanomedicine applications for IBD and address the current challenges and prospects in the field to advance nanomediated therapies in the future. Conclusion: Innovative NP-based treatment strategies promise a reliable and effective approach to IBD management.


Subject(s)
Colitis, Ulcerative , Crohn Disease , Inflammatory Bowel Diseases , Humans , Nanomedicine , Inflammatory Bowel Diseases/drug therapy , Colitis, Ulcerative/therapy , Crohn Disease/drug therapy , Crohn Disease/diagnosis , Drug Delivery Systems
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