[Extra-abdominal desmoid tumors. Diagnostic-therapeutic considerations and review of the literature]. / Tumores desmoides extraabdominales. Consideraciones diagnóstico-terapéuticas y revisión de la literatura.

The authors review the literature, discuss clinical aspects and options in the management of desmoid tumors, analyze recent advances in the understanding of its biology and how they affect therapeutic choices, and outline future treatment perspectives. We conclude that although recurrence rates are high, wide excision is the best firs approach. If it is not possible, marginal surgery and radiation therapy can be performed. Radiation therapy can be also use in the attempt to control recurrent disease. Although many pharmacologic agents have been advocated there is no clear proof of their usefulness. Systemic therapy may be considered for selected patients that are not amenable to local treatment.

Surgical treatment of the radial nerve lesions associated with fractures of the humerus.

Twelve patients who were surgically treated for radical nerve injuries associated with fractures of the humerus are reviewed. The average follow-up was 6 years (range 1-10). The mean time to full recovery was 19 months (range 12-40). Three fractures were open, and nine were closed. Seven of the fractures were located in the distal third of the humerus; two were in the middle third; two were segmental, involving both the middle and the distal thirds of the shaft; and one was supracondylar. All patients received initial treatment of the fracture in other medical units. The mean interval between the lesion and surgical treatment of the nerve injury was 6 months (range 25 days to 15 months). Perineural fibrosis at the lesion site was observed in four patients. Three nerves were found entrapped in the callus. In two cases the nerve was found to be partially divided, and in three cases a total section was observed. The techniques employed were microsurgical reconstruction with interfascicular grafting using sural nerve in six patients, neurolysis in five cases, and tendon transfers in one case. Excellent and good results were obtained in 91% of cases. In the case with a poor result, tendon transfers were made, with an acceptable functional result.