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2.
Zentralbl Bakteriol Orig A ; 240(4): 538-41, 1978 Jun.
Article in German | MEDLINE | ID: mdl-696061

ABSTRACT

The statistical analysis of results of the leukocyte migration inhibition test with polysaccharide antigen C of T. saginata in 49 patients with taeniasis and 20 healthy persons was performed. Examinations took place in two series: before medication (series I) and 7 days after treatment (series II). In the first series, a significant decrease in the migration index (0.42) was found in the patients' group as compared with that of the control group (0.92). In the second series, the migration index was subject to an increase (0.62) which, however, did not reach the value obtained in the control group. In both series, statistically significant differences in the indices of the test performed were observed between patients and the control group of healthy individuals. The results obtained in the present studies demonstrate that T. saginata invasion in human brings about the development of a cellular hypersensitivity reaction of delayed type which is revealed in the leukocyte migration inhibition test; the elimination of the parasite leads to an impairment of the effect of this reaction within a relatively short period.


Subject(s)
Cell Migration Inhibition , Macrophages/immunology , Polysaccharides, Bacterial/immunology , Taenia/immunology , Taeniasis/immunology , Adult , Diagnosis, Differential , Humans , Hypersensitivity, Delayed , Middle Aged , Taeniasis/diagnosis
5.
Zentralbl Bakteriol Orig A ; 239(3): 414-8, 1977 Nov.
Article in German | MEDLINE | ID: mdl-602519

ABSTRACT

In 49 patients suffering from taeniasis caused by T. saginata, the serum levels of the immunoglobulins, IgG, IgA, and IgM as well as the blastic lymphocyte transformation due to phytohaemagglutinin were determined. The studies were performed prior to treatment (1st testing) and at day 7 following administration of Yomesan (2nd testing). The results obtained were statistically evaluated by comparison with the results of control studies in 20 healthy persons. A statistically significant lowering of the IgA and IgM levels and of the percentage of blastic cells following lymphocyte stimulation by phytohaemagglutinin was demonstrated to be present in the patients by the 1st as well as the 2nd testing.


Subject(s)
Immunoglobulins/metabolism , Lymphocyte Activation , Taeniasis/immunology , Adult , Female , Humans , Immunoglobulin A/metabolism , Immunoglobulin G/metabolism , Immunoglobulin M/metabolism , Lectins/pharmacology , Male , Middle Aged , Niclosamide/therapeutic use , Taeniasis/drug therapy
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