ABSTRACT
Abnormal sleep-wake organization is frequently seen in idiopathic parkinsonism (PD) and other parkinsonism syndromes. A 1993 article in The Annals of Neurology first described the high rate of REM behavior disorder (RBD) in non-demented PD patients (1). In this article, we present the case reports of three non-demented PD patients who manifested RBD while on recommended doses of selegiline (Eldepryle). None of them had problems severe enough to suggest RBD while they were being treated with varying doses of other dopaminergic agents (carbidopa/L-dopa, pergolide) unaccompanied by selegiline.
Subject(s)
Parkinson Disease/drug therapy , Selegiline/pharmacology , Sleep, REM/drug effects , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Selegiline/therapeutic useABSTRACT
Weakness after exercise is not a commonly recognized major symptom of paramyotonia congenita. A patient with classic paramyotonia congenita developed thyrotoxicosis and severe weakness after exercise. This symptom resolved after the thyrotoxicosis was treated.
