ABSTRACT
Vaginal yolk sac tumors are rare pediatric malignant tumors and the most common form of vaginal germ-cell tumors in children. They are almost exclusively found in females under 3 years of age. Treatment involves local excision either with or without chemotherapy. Herein, we describe a case of a 3-year-old girl with vaginal Yolk sac tumor, who underwent buccal mucosa vaginoplasty through an anterior sagittal transrectal approach , as an effective oncological procedure, with preservation of reproductive function.
Subject(s)
Endodermal Sinus Tumor , Neoplasms, Germ Cell and Embryonal , Vaginal Neoplasms , Child , Female , Humans , Child, Preschool , Endodermal Sinus Tumor/surgery , Endodermal Sinus Tumor/drug therapy , Mouth Mucosa , Vagina/surgery , Vagina/pathology , Vaginal Neoplasms/drug therapyABSTRACT
Heparin-induced thrombocytopenia in pregnancy is an uncommon phenomenon which rarely occurs in the first trimester. Therapeutic options and duration of therapeutic anticoagulation are varied amongst reported published cases. We report a 41-year-old female with confirmed HIT following anticoagulation with dalteparin for deep vein thrombosis (DVT). She was treated with therapeutic fondaparinux for 3 months followed by prophylaxis dosage until delivery and for 6 weeks thereafter. A review of reported cases of the development of HIT in the first trimester and subsequent clinical management is discussed.
