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4.
Allergol Immunopathol (Madr) ; 25(4): 199-202, 1997.
Article in English | MEDLINE | ID: mdl-9269510

ABSTRACT

Authors studied nasal hypersensitivity (NH) behaviour on 41 subjects suffering from recurrent adenoids disease during their paediatric age. All subjects underwent clinical history, ENT examination, skin-test, RAST and non-specific nasal provocation test with histamine and assessment of the amount of sneezes. The results showed a familial transmission of the NH in 53.6% of cases, a hypogammaglobulinemia in 14.6% of cases. NH was present in 57% of subjects, much more with higher number of phlogosis, with higher possibility of familial transmission and with premature socialisation. These data showed a strict correlation between NH and recurrent adenoids disease. This NH didn't reduce in subjects undergone adenoidectomy and with time it conditioned the answer of the whole airways which could be noticed also in adulthood subjects. The presence of this NH had remarkable significance for diagnosis and therapeutic behaviour.


Subject(s)
Adenoids/surgery , Nose Diseases/complications , Respiratory Hypersensitivity/complications , Sneezing/drug effects , Adenoidectomy , Adenoids/pathology , Child , Child Day Care Centers , Child, Preschool , Disease Susceptibility , Female , Histamine/pharmacology , Humans , Hypertrophy , IgA Deficiency/complications , IgG Deficiency/complications , Incidence , Male , Nasal Provocation Tests , Nose Diseases/diagnosis , Postoperative Complications/epidemiology , Radioallergosorbent Test , Recurrence , Respiratory Hypersensitivity/diagnosis , Respiratory Tract Infections/epidemiology , Skin Tests
5.
Allergol Immunopathol (Madr) ; 22(6): 264-8, 1994.
Article in English | MEDLINE | ID: mdl-7892815

ABSTRACT

Ten patients with vasomotor rhinitis underwent local treatment with capsaicin (30 micromol.), once per week for five weeks; controls were carried out at weekly intervals and 1, 3 and 6 months after therapy. Assessment was made using symptom score and nasal resistance scores both basal and subsequent to aspecific nasal provocation. Results showed abatement of symptoms, and reduction of nasal resistance and aspecific hyperreactivity already during the second week. This trend continued for six months, with endoscopic improvement also. Hence, this treatment proved to be efficient in reducing nasal reactivity.


Subject(s)
Capsaicin/therapeutic use , Rhinitis, Vasomotor/drug therapy , Adolescent , Adult , Airway Resistance/drug effects , Capsaicin/pharmacology , Female , Humans , Male , Middle Aged , Nasal Mucosa/drug effects , Nasal Mucosa/metabolism , Nasal Provocation Tests , Nerve Fibers/drug effects , Pain/drug therapy , Pruritus/drug therapy , Rhinitis, Vasomotor/physiopathology , Sneezing/drug effects , Treatment Outcome
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