ABSTRACT
OBJECTIVE: To study the alkaloids of Voacanga africana. METHODS: The alkaloids were isolated by normal phase silica gel and Sephadex LH-20 column chromatography. Their structures were elucidated by analysis of spectroscopic data. RESULTS: Eight alkaloids were isolated and their structures were elucidated as voacangine(1), voacangine hydroxyindolenine(2), 19R-epi-voacristine(3), epi-ibogaine(4), vobasine(5), 19-epi-heyneanine(6), vobtusine(7) and voacamine(8). CONCLUSION: Compounds 2-4 and 6 are isolated from this plant for the first time.
Subject(s)
Alkaloids/chemistry , Voacanga/chemistry , Alkaloids/isolation & purification , Ibogaine/analogs & derivatives , Ibogaine/chemistry , Ibogaine/isolation & purification , Magnetic Resonance Spectroscopy , Plant Bark/chemistry , Plant Roots/chemistry , Plant Stems/chemistryABSTRACT
OBJECTIVE: To investigate the chemical constituents of Ardisia tenera Mez. METHODS: Compounds were isolated by normal phase silica gel, MCI GEL and Sephadex LH-20 gel column chromatography. Their structures were elucidated by analyses of spectroscopic data. RESULTS: Eight compounds were isolated, and their structures were elucidated as bauerenol (I), myristic acid (II), 11-phenyl-1-(2',6'-dihydroxy-4'-methoxy-phenyl)-undecan-1 -one (III), ardisinone A( IV), ardisinone B( V ), ardisinone C( VI), ardisinone F (VI), beta-sitosterol (VIII). CONCLUSION: All of these compounds are obtained from this plant for the first time.
