ABSTRACT
OBJECTIVE: To investigate prostate cancer detection rate of different biopsy protocols in different PSA value groups in rural China. METHODS: A total of 186 patients underwent contrast-enhanced ultrasound (CEUS) in order to determine the puncture target prior to biopsy were enrolled in this retrospective study. All patients underwent 12-core SB combined with CEUS-TB. The biopsy results of different biopsy protocols were compared in patients with stratification by PSA value. RESULTS: Among the 186 patients underwent prostate biopsy, the histopathologic results revealed prostate cancer (PCa) in 117 cases (62.9%) and benign lesions in 69 cases (37.1%). The PCa detection rate between 8-core SB and 12-core SB showed no significant difference in PSA 4-10âng/ml group, while the 12-core SB was significantly higher than CEUS-TB (44.9% versus 32.7%, Pâ=â0.01). In PSA 10-20âng/ml group, the significant difference was not seen between SB and CEUS-TB (50.0% versus 45.7%, Pâ=â0.15). As for PSA greater than 20âng/ml group, the PCa detection rate by SB was higher than CEUS-TB, but showed no statistically significance (79.1% versus 76.9%, Pâ=â0.15). In the overall patients, the biopsy core positive rate of CEUS-TB was significantly higher than SB (97% versus 55.5% and 28.5%, Pâ=â0.0001). CONCLUSION: The flexible use of SB combined with CEUS-TB can reduce the number of biopsy cores in higher PSA groups. It has clinical importance in the detection of PCa in different PSA value groups in rural China.
Subject(s)
Contrast Media/therapeutic use , Image-Guided Biopsy/methods , Prostate-Specific Antigen/metabolism , Prostatic Neoplasms/diagnostic imaging , Ultrasonography/methods , Aged , Biopsy , China , Humans , Male , Prostatic Neoplasms/pathology , Retrospective Studies , Rural PopulationABSTRACT
BACKGROUND: This study aims to investigate the value of oral contrast ultrasonography (OCUS) in the diagnosis of gastric cancer in elderly patients. METHODS: OCUS data obtained from patients ≥ 60 years old were retrospectively analyzed and compared with gastroscopy results. RESULTS: Among the 12,716 subjects examined by OCUS, 5021 subjects were ≥ 60 years old, which accounted for 39.48% (5021/12,716). Gastritis, gastric polyp, benign ulcer, and gastric cancer were detected by OCUS in 1099 patients. Among them, 196 patients underwent gastroscopy. Furthermore, ulcerative lesions were detected in 32 patients by OCUS and in 51 patients by gastroscopy, and the coincidence rate was 62.74%. Among these patients, gastric cancer was diagnosed in 18 patients by OCUS with a detection rate of 1.64% (18/1099) and detected in 19 patients by gastroscopy with a diagnostic coincidence rate of 94.73% (18/19). Furthermore, benign ulcer was detected in 14 patients by OCUS and in 32 patients by gastroscopy, and the diagnostic coincidence rate was 43.75% (14/32). CONCLUSION: OCUS helps to timely detect senile gastric cancer and can be used as a suitable technique for the detection of gastric diseases.
Subject(s)
Contrast Media/administration & dosage , Early Detection of Cancer/methods , Stomach Neoplasms/diagnostic imaging , Ultrasonography/methods , Adenomatous Polyps/diagnostic imaging , Adenomatous Polyps/epidemiology , Age Factors , Aged , Aged, 80 and over , Comorbidity , Feasibility Studies , Female , Gastritis/diagnostic imaging , Gastritis/epidemiology , Gastroscopy , Humans , Incidence , Male , Middle Aged , Predictive Value of Tests , Prognosis , Retrospective Studies , Stomach Neoplasms/epidemiology , Stomach Ulcer/diagnostic imaging , Stomach Ulcer/epidemiologyABSTRACT
OBJECTIVE: To investigate the clinical value of contrast-enhanced ultrasonography (CEUS) in the diagnosis of prostate cancer in patients with different concentrations of prostate-specific antigen (PSA). METHODS: Based on the PSA concentration, 186 patients were divided into three groups (PSA 4ï¼10 µg/L, 11ï¼20 µg/L, and >20 µg/L) and underwent transrectal CEUS and biopsy. We compared the pathological results with the CEUS features in different groups of patients and performed a statistical analysis on the characteristics of the CEUS manifestations of prostate cancer and benign prostatic lesions. RESULTS: Of the 186 patients, 118 (63.4%) were diagnosed by biopsy with prostate cancer and the other 68 (36.6%) with benign prostatic lesions. The positive rate of CEUS in the diagnosis of prostate cancer was above 95% in all the three groups, significantly higher than that of conventional ultrasound in the PSA 4ï¼10 and >10ï¼20 µg/L groups (P <0.01). CONCLUSIONS: Contrast-enhanced ultrasonography can achieve a high detection rate in the diagnosis of prostate cancer, especially for the patients with a low PSA concentration, and therefore can be used as one of the most valuable diagnostic techniques for this purpose.
Subject(s)
Contrast Media , Prostate-Specific Antigen/blood , Prostatic Neoplasms/blood , Prostatic Neoplasms/diagnostic imaging , Ultrasonography/methods , Biopsy , Humans , Male , Prostate/diagnostic imaging , Prostate/pathology , Prostatic Diseases/blood , Prostatic Diseases/diagnostic imaging , Prostatic Diseases/pathology , Prostatic Neoplasms/pathology , Ultrasonography/statistics & numerical dataABSTRACT
OBJECTIVE: To study the value of high-frequency ultrasound in the diagnosis of duchenne muscular dystrophy diseases (DMD) in children. METHODS: Eight children with DMD were enrolled as DMD group and 10 healthy children as the control group. The echogenicity of the rectus femoris muscle and the gap between the gastrocnemius and soleus muscles in the two groups were detected by high-frequency ultrasound. RESULTS: Compared with the control group, rectus femoris and gastrocnemius muscles in the DMD group showed increased echogenicity and their muscle fibers were arranged irregularly, and the gap between the gastrocnemius and soleus muscles became wilder (P<0.01). CONCLUSIONS: High-frequency ultrasound is valuable in the diagnosis of DMD.
