[Information analysis of development of researches on global neglected tropical diseases].

OBJECTIVE: To reveal the development and evolution pathway of global neglected tropical diseases (NTDs) from the bibliometrics and information visualization perspective. METHODS: The research publications on the subject of NTDs from Web of Science, PubMed and PLoS NTD were retrieved and analyzed by using the bibliometrics analysis, visualization analysis and citation strategic diagrams. RESULTS: The number of publications on the subject of NTDs from 2005 to 2013 had being growing gradually year by year, but there were some differences from disease to disease. The distribution of the authors, organizations and countries of the publications could be classified into two clusters, one was represented by US and UK and the other was represented by Switzerland and China. The research subjects of the publications contained epidemiology, laboratory and social economics based on population and animals. Six key and hot topics were revealed as follows: the disease burden; incorporating the control of NTDs into the programs of HIV/AIDS, tuberculosis, and malaria; comprehensive control strategies and their influence factors; human chemotherapy and its influence factors; vaccine; research and development innovation. CONCLUSION: The NTDs research in the globe is on its developing way with both challenges and opportunities, more concerns and investments, as well as the cooperations among different countries, organizations and disciplines are needed.

[Evolution of schistosomiasis control and prevention strategies in hilly regions with schistosomiasis endemic in China].

This article expatiates the epidemiological characteristics, the evolution process of control and prevention strategies and measures in hilly regions with schistosomiasis endemic, especially the research progress and obstacle factors existed in the implementation process of the comprehensive strategy focused on controlling infection source, aiming at providing references for the hilly regions to reach transmission interrupted standard.

[Obstacle factors in implementation of integrated schistosomiasis prevention and control strategies with emphasis on infectious source in hilly endemic regions].

OBJECTIVE: To analyze the main obstacles existing in the implementation of integrated schistosomiasis prevention and control strategies with emphasis on infection source in hilly endemic regions, and to find out the current priority issues in schistosomiasis prevention and control, so as to provide the evidence for further solutions. METHODS: Two typical hilly schistosomiasis endemic regions in Sichuan Province, including Pujiang County of Chengdu City and Dongpo District of Meishan City, were selected as research areas. A framework of obstacle factors in the implementation of integrated schistosomiasis prevention and control strategies with emphasis on infectious source in hilly endemic regions was built by literature review, and the management and technical personnel who worked on schistosomiasis prevention and control in eight different industries (health, agriculture, forestry and so on) and five levels (provincial, city, county, township and village levels) were investigated by questionnaires in the way of nominal group. RESULTS: One hundred and fifty-three management and technical personnel in different industries and different levels were investigated. The questionnaire recovery rate (experts' positive coefficient) was 100%. The results showed that the first four problems needing to be concerned in the implementation of integrated schistosomiasis prevention and control strategies with emphasis on infection source were eliminating Oncomelania hupensis snails by projects, health education, examination and treatment for schistosomiasis persons, and harmless treatment of night-soil and safe water supply. The focuses of two counties in the implementation of integrated strategy measures were different. The harmless treatment of night-soil and safe water supply was the most important measure in Pujiang County, while the elimination of snails by projects was the most in Dong-po District. CONCLUSIONS: As the differences in the situation of epidemic areas and the existed condition of the prevention and treatment progress, the comprehensive schistosomiasis control measures should be adjusted according to the local conditions in the implementation of integrated schistosomiasis prevention and control strategies with emphasis on infection source.