[Investigation of psychological state and its influencing factors in children with epilepsy].

OBJECTIVE: To evaluate the psychological state of children with epilepsy and analyze its influencing factors. METHODS: The Mental Health Scale for Child and Adolescent was used to survey 113 children with epilepsy and 114 normal children to evaluate and compare their psychological state. Questionnaires were used to investigate the general status of all subjects and the disease condition and treatment of children with epilepsy. The possible influencing factors for the psychological state of children with epilepsy were analyzed. RESULTS: The mental health status of children with epilepsy was poorer than that of normal children in cognition, thinking, emotion, will-behavior, and personality traits (P<0.05). Multivariate logistic regression analysis showed that family education, family relations, seizure frequency, seizure duration, EEG epileptiform discharges in the last six months, and number of types of antiepileptic drugs were correlated with the psychological state of children with epilepsy. CONCLUSIONS: There is a wider range of psychological health problems in children with epilepsy than in normal children. Poor family living environment, poor seizure control, and use of many antiepileptic drugs are the risk factors affecting the psychological state of children with epilepsy. Improving family living environment, controlling seizures, and monotherapy help to improve the psychological state of children with epilepsy.

Clinical analysis of intracranial hemorrhage in children with hemophilia / 中华实用儿科临床杂志

Objective To discuss the risk factors,clinical characteristics,treatment protocol and prognosis of intracranial hemorrhage (ICH) in children with hemophilia.Methods Twenty-four hemophilic children with ICH,which were registered in hospital between Jan.2005 and Dec.2012,were reviewed retrospectively.Results (1) Fifteen patients were hemophilia A and 9 patients were hemophilia B,all boys.The mean age of ICH was 1 year and 7 months old.The 70.8％ of patients were less than 3 years old,among whom hemophilia was diagnosed after ICH in more than 88.9％.The 87.5％ of patients had moderate or severe disease,and 37.5％ had head trauma before ICH.(2) The clinical symptoms were high cranial pressure,anemia,disturbance of consciousness,seizure,hemiplegia.(3) ICH position:cerebral hemorrhage with subarachnoid hemorrhage (SAH) in 7 patients,ventricular hemorrhage 2 patients,subdural hemorrhage with SAH in 10 patients,extradural hemorrhage 5 patients.(4)All patients were given blood coagulation factor replacement therapy,5 patients by operation.(5)Thirteen patients had not sequelae,9 patients had sequelae and 2 patients died.Conclusions The risk factors of ICH in hemophilic children include ages less than 3 years old,moderate or severe disease.Some patients have no predispositions.The clinical symptoms of patients are similar with normal children suffering from ICH.The keys of treatment are early diagnosis,early treatment and adequate course of treatment.Surgical operation could be in treatment after coagulation function gets corrected back to normal.