Birth Outcomes of Pregnant Women Infected with COVID-19 in Highland Areas of China from 2020 to 2022: A Retrospective Analysis.

Purpose: To explore the effect of coronavirus disease 2019 (COVID-19) infection on neonates in plateau regions. Methods: Cases of newborns born to pregnant women infected with COVID-19 who received prenatal care or treatment at the Women and Children's Hospital of the Tibet Autonomous Region and the Lhasa People's Hospital between January 2020 and December 2022 (infected group) and newborns born to healthy pregnant women (non-infected group) who were included by age, underlying disease and length of hospital stay were retrospectively collected. According to the inclusion and exclusion criteria, 381 patients in the infected group and 314 patients in the non-infected group were included in the study. Results: The results of multivariate analysis showed that admission to the neonatal intensive care unit (OR = 3.342, 95% CI = 1.564-6.764), shortness of breath (OR = 2.853, 95% CI = 1.789-3.154), irregular breathing (OR = 2.465, 95% CI = 1.879-4.112) and neonatal jaundice (OR = 2.324, 95% CI = 1.989-2.445) were the factors influencing the low Apgar scores of neonates in the infected group (all P < 0.05). Conclusion: Neonates born to pregnant women infected with COVID-19 had lower Apgar scores and higher incidences of complications, such as shortness of breath, groaning, irregular breathing and neonatal jaundice, than newborns born to pregnant women not infected with COVID-19.

Construction of a molecular structure model of mild-oxidized Chinese lignite using Gaussian09 based on data from FTIR, solid state 13C-NMR.

Great progress has been made in the detection of fractions from oxidized lignite, but no molecular structures are reported. A molecular structure model of oxidized Shengli lignite was constructed using ultimate analysis, 13C nuclear magnetic resonance spectrum (NMR), and Fourier transform infrared spectroscopy (FTIR). Parameters are derived from PeakFit4.12 and MestReNova software. Gaussian09 software was used to optimize the model and calculate the FTIR, and the calculated spectrogram is consistent with the experimental one. The molecular formula of the structure model was C96H95O45N, and aromatic rings were mainly linked by oxygen containing functional groups. The electrostatic potential of the structure model was analyzed to explain the great solubility and a good deal of carboxyl acids.